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Home / Primary Antibodies

Anti-FBXW4 Antibody

SKU : BHA10900646

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Applied Biological Materials (abm) Inc.

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Mfr.No.	Y158331
Categories	Primary Antibodies
Clonality	polyclonal
Description	This gene is a member of the F-box/WD-40 gene family, which recruit specific target proteins through their WD-40 protein-protein binding domains for ubiquitin mediated degradation. In mouse, a highly similar protein is thought to be responsible for maintaining the apical ectodermal ridge of developing limb buds; disruption of the mouse gene results in the absence of central digits, underdeveloped or absent metacarpal/metatarsal bones and syndactyly. This phenotype is remarkably similar to split hand-split foot malformation in humans, a clinically heterogeneous condition with a variety of modes of transmission. An autosomal recessive form has been mapped to the chromosomal region where this gene is located, and complex rearrangements involving duplications of this gene and others have been associated with the condition. A pseudogene of this locus has been mapped to one of the introns of the BCR gene on chromosome 22. [provided by RefSeq, Jul 2008]
Host	Rabbit
Immunogen	Rabbit polyclonal FBXW4 (1) antibody was raised against a recombinated human FBXW4 protein 5-186aa (BC007380).
Quantity	100 µl
Reactivity	Human
Recombinant	FALSE
Regulatory	RUO
Shipping Condition	Ice Packs

Buffer	PBS, pH 7.4 with 0.02% Sodium Azide
Concentration	100µg/100ul
Format	Liquid
Purity	Affinity purified
Storage	This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20°C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.
Storage Condition	-20C

Applications	WB, IHC, ELISA
Description	WB ; IHC ; ELISA

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SKU	Supplier No.	Size	Your price	Quantity
BHA10900646	Y158331	100 ul	$217.50		Add to Cart

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