Coagulation factor XIII A chain ; Coagulation factor XIII A1 polypeptide ; Coagulation factor XIIIa ; F13A ; F13a1 ; Factor XIIIA ; Fibrin stabilizing factor, A subunit ; Fibrinoligase ; FSF, A subunit ; Protein-glutamine gamma-glutamyltransferase A chain
Categories
Primary Antibodies
Cellular Localization
Cytoplasmic (Secreted)
Chromosome Location
6p25.3-p24.3
Clonality
Monoclonal
Description
It recognizes a protein of 83kDa, which is identified as Factor XIIIa. It has been identified in platelets, megakaryocytes, and fibroblast-like mesenchymal or histiocytic cells in the placenta, uterus, and prostate, monocytes and macrophages and dermal dendritic cells. Anti-factor XIIIa has been found to be useful in differentiating between dermatofibroma (almost all cases are positive), dermatofibrosarcoma protuberans (-/+) and desmoplastic malignant melanoma (-). Anti-factor XIIIa positivity is also seen in capillary hemagioblastoma, hemangioendothelioma, hemangiopericytoma, xanthogranuloma, xanthoma, hepatocellular carcinoma, glomus tumor, and meningioma.
Host
Mouse
Immunogen
Recombinant fragment of human Factor XIIIa protein (aa46-181) (exact sequence is proprietary)
Isotype
IgG2b Kappa
Positive Control
293T Cells. Placenta.
Reactivity
Human
Recombinant
FALSE
Regulatory
RUO
Swissprot
P00488
Uniprot
335513
Gene Id
2162
Buffer
200μg/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Concentration
1.0mg/ml
Description
There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Purity
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
Applications
ELISA, FACS, IF, IHC-F
Description
(Staining of formalin-fixed tissues requires boiling tissue sections in 10mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined., ELISA ; FACS ; IF ; IHC-F
Dilution
ELISA
For coating, order Ab without BSA
FACS
0.5-1μg/million cells
IF
0.5-1μg/ml
IHC-F
1-2μg/ml for 30 min at RT
Reviews of Anti-Factor XIIIa (Coagulation Factor XIIIA Chain) Antibody BHA10201061