Anti-extracellular superoxide dismutase (SOD3 18-37) Antibody

Mfr.No.	Y075074
Categories	Primary Antibodies
Clonality	polyclonal
Description	SOD3 is a member of the superoxide dismutase protein family. SODs are antioxidant enzymes that catalyse the dismutation of two superoxide radicals into hydrogen peroxide and oxygen. SOD3 is thought to protect the brain, lungs and other tissues from oxidative stress. It is secreted into the extracellular space and forms a glycosylated homotetramer that is anchored to the extracellular matrix and cell surfaces through an interaction with heparan sulfate proteoglycan and collagen. A small percentage of SOD3 is cleaved near the C-terminus before secretion to generate circulating tetramers that do not interact with the extracellular matrix.
Host	Rabbit
Immunogen	A synthetic peptide (WTGEDSAEPNSDSAEWIRD) corresponding to the amino acids 18-37 of human extracellular superoxide dismutase conjugated to diphtheria toxin has been used as the immunogen.
Quantity	100 µl
Reactivity	Human
Recombinant	FALSE
Regulatory	RUO
Shipping Condition	Ice Packs

Buffer	PBS, pH 7.4 with 0.02% sodium azide.
Concentration	1µg/ul
Description	Specificity: This antibody has been shown to be specific for extracellular superoxide dismutase protein.
Format	Liquid
Purity	Filter purified
Storage	This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20°C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.
Storage Condition	-20C

Applications

WB, IHC

Description

This antibody works superbly in Immunohistochemistry on frozen or paraffin embedded tissues. Antigen retrieval has been used in testing but may not be necessary. Typical working dilutions for routine immunohistochemistry are 1: 100 to 1: 2000 depending on tissue and detection method. For western blotting a dilution range of 1: 1000 to 1: 4000 is recommended. The optimal dilution should be determined by the end user. This antibody stains prominently specific human airway (probably Clara cells) and alveolar type II cells and some tubular cells in the kidney. Other tissues have not yet been tested but the gene expression has also been reported in heart, pancreas and placenta., WB ; IHC

Dilution

IHC	1:100-1:2000
WB	1:1000-1:4000

Have you used this product?

Rate it now..!!

SKU	Supplier No.	Size	Your price	Quantity
BHA10903174	Y075074	100 ul	$802.50		Add to Cart

Anti-extracellular superoxide dismutase (SOD3 18-37) Antibody

Contact us to order

Tel

Email

Contact us to order

Tel

Email

Reviews of Anti-extracellular superoxide dismutase (SOD3 18-37) Antibody

Rate it now..!!