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Home / Primary Antibodies / Monoclonal Antibodies

Anti-eRF1/ETF1 Antibody Picoband® (monoclonal, 3B6)

SKU : BHA21003103

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Mfr.No.	M04157, M04157-10ug, M04157-Biotin, M04157-Cy3, M04157-Dylight488, M04157-Dylight550, M04157-Dylight594, M04157-FITC, M04157-HRP, M04157-APC, M04157-PE, M04157-iFluor647, M04157-carrier-free
Alternative Names	ribonuclease/angiogenin inhibitor 1
Background	Eukaryotic translation termination factor 1 (eRF1), also known asTB3-1, is a protein that in humans is encoded by the ETF1 gene. It is mapped to 5q31.2. This gene encodes a class-1 polypeptide chain release factor. The encoded protein plays an essential role in ing termination of mRNA translation from the termination codons UAA, UAG and UGA. This protein is a component of the SURF complex which promotes degradation of prematurely terminated mRNAs via the mechanism of nonsense-mediated mRNA decay (NMD). Alteate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 6, 7, and X.
Clonality	Monoclonal
Cross Reactivity	No cross-reactivity with other proteins.
Description	Boster Bio Anti-eRF1/ETF1 Antibody Picoband® (monoclonal, 3B6) catalog # M04157. Tested in Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Ribonuclease inhibitor which inhibits RNASE1, RNASE2 and ANG. May play a role in redox homeostasis.
Host	Mouse
Immunogen Region	E.coli-derived human eRF1/ETF1 recombinant protein (Position: D9-K342).
Isotype	Mouse IgG2a
Molecular Weight	49 kDa
Reactivity	Human, Mouse, Rat
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Synonyms	AW546468 antibody; C80305 antibody; MGC18200 antibody; MGC4569 antibody; MGC54054 antibody; OTTHUMP00000147628 antibody; OTTHUMP00000229864 antibody; OTTHUMP00000229865 antibody; OTTHUMP00000229866 antibody; OTTHUMP00000229870 antibody; OTTHUMP00000229871 antibody; OTTHUMP00000229872 antibody; Placental ribonuclease inhibitor antibody; Placental RNase inhibitor antibody; PRI antibody; RAI antibody; RI antibody; Ribonuclease inhibitor antibody; Ribonuclease/angiogenin inhibitor 1 antibody; Ribonuclease/angiogenin inhibitor antibody; RINI_HUMAN antibody; RNase inhibitor antibody; RNH 1 antibody; RNH antibody; RNH1 antibody; Rnh1 ribonuclease/angiogenin inhibitor 1 antibody
Note	Each vial contains 4mg Trehalose, 0.9mg NaCl and 0.2mg Na2HPO4.

Uniprot	P62495
Gene Id	2107
Gene Name	ETF1
Clone No	Clone: 3B6
Subcellular Location	Cytoplasm.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	WB, IHC, ICC, IF, Flow Cytometry
Description	Weste blot, 0.25-0.5ug/ml, Human, Mouse, Rat<br> Immunohistochemistry (Paraffin-embedded Section), 2-5ug/ml, Human, Rat<br> Immunocytochemistry/Immunofluorescence, 5ug/ml, Human<br> Flow Cytometry (Fixed), 1-3ug/1x10<sup>6</sup> cells, Human, Mouse, Rat<br>

Reference	1. Frolova, L., Le Goff, X., Rasmussen, H. H., Cheperegin, S., Drugeon, G., Kress, M., Arman, I., Haenni, A.-L., Celis, J. E., Philippe, M., Justesen, J., Kisselev, L. A highly conserved eukaryotic protein family possessing properties of polypeptide chain release factor. Nature 372: 701-703, 1994.<br /><br />2. Guenet, L., Henry, C., Toutain, B., Dubourg, C., Le Gall, J. Y., David, V., Le Treut, A. Eukaryotic translation termination factor gene (ETF1/eRF1) maps at D5S500 in a commonly deleted region of chromosome 5q31 in malignant myeloid diseases. Cytogenet. Cell Genet. 88: 82-86, 2000.<br /><br />3. Hansen, L. L., Jakobsen, C. G., Justesen, J. Assignment of the human translation termination factor 1 (ETF1) to 5q31.1 and of the proximal marker D5S1995 by radiation hybrid mapping. Cytogenet. Cell Genet. 87: 256-257, 1999.

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21003103-1	M04157	-	100 ug	$370		Add to Cart
BHA21003103-2	M04157-10ug	Sample	10 ug	$99		Add to Cart
BHA21003103-3	M04157-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21003103-4	M04157-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21003103-5	M04157-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21003103-6	M04157-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21003103-7	M04157-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21003103-8	M04157-FITC	FITC	100 ug	$570		Add to Cart
BHA21003103-9	M04157-HRP	HRP	100 ug	$570		Add to Cart
BHA21003103-10	M04157-APC	APC	100 ug	$670		Add to Cart
BHA21003103-11	M04157-PE	PE	100 ug	$670		Add to Cart
BHA21003103-12	M04157-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21003103-13	M04157-carrier-free	carrier-free	100 ug	$370		Add to Cart

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