This MAb reacts with a cytoplasmic domain of EGFR. EGFR is a type I receptor tyrosine kinase with sequence homology to erbB-1, -2, -3 -4 or HER-1, -2, -3 -4. It binds to Epidermal Growth Factor (EGF), Transforming Growth Factor-a (TGF-a), Heparin-binding EGF (HB-EGF), amphiregulin, βcellulin & epiregulin.
Host
Mouse
Immunogen
Purified EGFR from A431 cells.
Isotype
IgG1
Positive Control
A431 cells, Breast or Bladder cancer
Reactivity
Human
Recombinant
FALSE
Regulatory
RUO
Swissprot
P00533
Uniprot
488293
Gene Id
1956
Buffer
200μg/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA; 0.05% azide. Also available WITHOUT BSA; azide at 1.0mg/ml.
Concentration
1.0mg/ml
Description
There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Purity
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
Applications
IP, WB
Description
Optimal dilution for a specific application should be determined., IP ; WB
Dilution
IP
1-2 �g/500ug protein Lysate
WB
0.5-1.0μg/ml for 2 hours at RT
Reviews of Anti-EGFR (Epidermal Growth Factor Receptor) Antibody BHA10200887