This gene encodes a member of the Polycomb-group (PcG) family. PcG family members form multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes over successive cell generations. This protein interacts with enhancer of zeste 2, the cytoplasmic tail of integrin beta7, immunodeficiency virus type 1 (HIV-1) MA protein, and histone deacetylase proteins. This protein mediates repression of gene activity through histone deacetylation, and may act as a specific regulator of integrin function. Two transcript variants encoding distinct isoforms have been identified for this gene.
Host
Rabbit
Immunogen
A synthetic peptide of human EED
Isotype
IgG
Quantity
100µg 50kDa
Reactivity
Rat, Mouse, Human
Recombinant
TRUE
Regulatory
RUO
Shipping Condition
Ice Packs
Weight
50kDa
Buffer
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration
1mg/ml
Description
Specificity: Western blot analysis of extracts of various cell lines, using EED antibody.
Format
Liquid
Purity
Affinity purification
Storage
Store at -20oC (regular) and -80oC (long term). Avoid freeze / thaw cycles.