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Home / Primary Antibodies

Anti-DP1 receptor Antibody

BHA10918217
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Contact us to order
Tel
+1 866.986.9598
Email
orders@biohippo.com
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Buffer PBS, pH 7.4 with 0.02% sodium azide.
Concentration 1µg/ul
Description Specificity: This Polyclonal antibody is directed against human DP1 receptor protein. The product was purified from seurm by protein A chromatography. Expect reactivity with human DP1 receptor. Cross-reactivity with DP1 receptor from other sources has not been determined.
Relevance: The DP1 receptor is one of two receptor isoforms for prostaglandin D2 (PGD ), a major cyclooxygenase metabolite of arachidonic acid. As a G-protein coupled receptor (GPCR), the receptor primarily couples to Gs to increase cAMP, but also transiently increases Ca2+, apparently through the cAMP pathway(1). DP1 receptor mRNA has been detected in various tissues and cells including brain, spleen, lung, bone marrow, stomach, skin, and mast cells(2), however little is know about its protein localization due to its low level of expression. DP1 receptor polyclonal antibody detects the protein by western blot in samples such as cerebral cortex, hippocampus, and HT-29 cells, the only colorectal cancer cell line shown to express this receptor(3). The antibody can also be used in immunocytochemistry /immunohistochemistry to detect DP1 receptor expression in cells and tissues.
Format Liquid
Purity Affinity purified
Storage This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20°C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.
Storage Condition -20C
Applications WB
Description Recommended dilutions
WB: 1/1000.
Predicted molecular weight: 43 kDa.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user., WB
Dilution

WB1:1000
SKU Supplier No. Size Your price Quantity
BHA10918217 Y080009 100 ul $187.50
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