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Home / Primary Antibodies / Polyclonal Antibodies

Anti-DNAJC6 Antibody Picoband®

SKU : BHA21003042

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Mfr.No.	A05616-2, A05616-2-10ug, A05616-2-Biotin, A05616-2-Cy3, A05616-2-Dylight488, A05616-2-Dylight550, A05616-2-Dylight594, A05616-2-FITC, A05616-2-HRP, A05616-2-APC, A05616-2-PE, A05616-2-iFluor647, A05616-2-carrier-free
Alternative Names	JunD proto-oncogene, AP-1 transcription factor subunit
Background	Putative tyrosine-protein phosphatase auxilin is an enzyme that in humans is encoded by the DNAJC6 gene. DNAJC6 belongs to the evolutionarily conserved DNAJ/HSP40 family of proteins, which regulate molecular chaperone activity by stimulating ATPase activity. DNAJ proteins may have up to 3 distinct domains: a conserved 70-amino acid J domain, usually at the N terminus, a glycine/phenylalanine (G/F)-rich region, and a cysteine-rich domain containing 4 motifs resembling a zinc finger domain (Ohtsuka and Hata, 2000
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins.
Description	Boster Bio Anti-DNAJC6 Antibody Picoband® catalog # A05616-2. Tested in ELISA, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Transcription factor binding AP-1 sites.
Host	Rabbit
Immunogen Region	E.coli-derived human DNAJC6 recombinant protein (Position: R32-Y913).
Isotype	Rabbit IgG
Molecular Weight	120 kDa
Reactivity	Human, Mouse, Rat
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Synonyms	Transcription factor jun-D; JUND
Note	Each vial contains 4mg Trehalose, 0.9mg NaCl and 0.2mg Na2HPO4.

Uniprot	O75061
Gene Id	9829
Gene Name	DNAJC6
Subcellular Location	Nucleus.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	ELISA, IF, IHC, ICC, WB
Description	Weste blot, 0.1-0.25ug/ml, Human, Mouse, Rat<br> Immunohistochemistry (Paraffin-embedded Section), 2-5ug/ml, Rat<br> Immunocytochemistry/Immunofluorescence, 5ug/ml, Human<br> ELISA, 0.1-0.5ug/ml, -<br>

Reference	1. Edvardson, S., Cinnamon, Y., Ta-Shma, A., Shaag, A., Yim, Y.-I., Zenvirt, S., Jalas, C., Lesage, S., Brice, A., Taraboulos, A., Kaestner, K. H., Greene, L. E., Elpeleg, O. A deleterious mutation in DNAJC6 encoding the neuronal-specific clathrin-uncoating co-chaperone auxilin, is associated with juvenile parkinsonism. PLoS One 7: e36458, 2012. Note: Electronic Article.<br /><br />2. Elsayed, L. E. O., Drouet, V., Usenko, T., Mohammed, I. N., Hamed, A. A. A., Elseed, M. A., Salih, M. A. M., Koko, M. E., Mohamed, A. Y. O., Siddig, R. A., Elbashir, M. I., Ibrahim, M. E., Durr, A., Stevanin, G., Lesage, S., Ahmed, A. E., Brice, A. A novel nonsense mutation in DNAJC6 expands the phenotype of autosomal-recessive juvenile-onset Parkinson's disease. (Letter) Ann. Neurol. 79: 335-338, 2016.<br /><br />3. Fotin, A., Cheng, Y., Grigorieff, N., Walz, T., Harrison, S. C., Kirchhausen, T. Structure of an auxilin-bound clathrin coat and its implications for the mechanism of uncoating. Nature 432: 649-653, 2004.

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21003042-1	A05616-2	-	100 ug	$370		Add to Cart
BHA21003042-2	A05616-2-10ug	Sample	10 ug	$99		Add to Cart
BHA21003042-3	A05616-2-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21003042-4	A05616-2-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21003042-5	A05616-2-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21003042-6	A05616-2-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21003042-7	A05616-2-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21003042-8	A05616-2-FITC	FITC	100 ug	$570		Add to Cart
BHA21003042-9	A05616-2-HRP	HRP	100 ug	$570		Add to Cart
BHA21003042-10	A05616-2-APC	APC	100 ug	$670		Add to Cart
BHA21003042-11	A05616-2-PE	PE	100 ug	$670		Add to Cart
BHA21003042-12	A05616-2-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21003042-13	A05616-2-carrier-free	carrier-free	100 ug	$370		Add to Cart

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