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Home / Primary Antibodies / Polyclonal Antibodies

Anti-DHPS/DHS Antibody Picoband®

SKU : BHA21003337

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Mfr.No.	A02106-2, A02106-2-10ug, A02106-2-Biotin, A02106-2-Cy3, A02106-2-Dylight488, A02106-2-Dylight550, A02106-2-Dylight594, A02106-2-FITC, A02106-2-HRP, A02106-2-APC, A02106-2-PE, A02106-2-iFluor647, A02106-2-carrier-free
Alternative Names	adrenoceptor beta 3
Background	Deoxyhypusine synthase is an enzyme that in humans is encoded by the DHPS gene. This gene encodes a protein that is required for the formation of hypusine, a unique amino acid formed by the posttranslational modification of only one protein, eukaryotic translation initiation factor 5A. The encoded protein catalyzes the first step in hypusine formation by transferring the butylamine moiety of spermidine to a specific lysine residue of the eukaryotic translation initiation factor 5A precursor, forming an intermediate deoxyhypusine residue. Alteatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins.
Description	Boster Bio Anti-DHPS/DHS Antibody Picoband® catalog # A02106-2. Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. Beta-3 is involved in the regulation of lipolysis and thermogenesis.
Host	Rabbit
Immunogen Region	E.coli-derived human DHPS recombinant protein (Position: F54-K358).
Isotype	Rabbit IgG
Molecular Weight	41 kDa
Reactivity	Human, Mouse, Rat
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Synonyms	Beta-3 adrenergic receptor; Beta-3 adrenoreceptor; Beta-3 adrenoceptor; ADRB3; ADRB3R; B3AR
Tissue Specificity	Expressed mainly in adipose tissues.
Note	Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4.

Uniprot	P49366
Gene Id	1725
Gene Name	DHPS
Subcellular Location	Cell membrane. Multi-pass membrane protein.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	WB, IHC, ICC, IF, Flow Cytometry, ELISA
Description	Weste blot, 0.25-0.5ug/ml, Human, Mouse, Rat<br> Immunohistochemistry (Paraffin-embedded Section), 2-5ug/ml, Human<br> Immunocytochemistry/Immunofluorescence, 5ug/ml, Human<br> Flow Cytometry (Fixed), 1-3ug/1x10<sup>6</sup> cells, Human<br> ELISA, 0.1-0.5ug/ml, -<br>

Reference	1. Bevec, D., Kappel, B., Jaksche, H., Csonga, R., Hauber, J., Klier, H., Steinkasserer, A. Molecular characterization of a cDNA encoding functional human deoxyhypusine synthase and chromosomal mapping of the corresponding gene locus. FEBS Lett. 378: 195-198, 1996. <br /><br />2. Ganapathi, M., Padgett, L. R., Yamada, K., Devinsky, O., Willaert, R., Person, R., Au, P.-Y. B., Tagoe, J., McDonald, M., Karlowicz, D., Wolf, B., Lee, J., and 10 others. Recessive rare variants in deoxyhypusine synthase, an enzyme involved in the synthesis of hypusine, are associated with a neurodevelopmental disorder. Am. J. Hum. Genet. 104: 287-298, 2019. <br /><br />3. Hauber, I., Bevec, D., Heukeshoven, J., Kratzer, F., Ho, F., Choidas, A., Harrer, T., Hauber, J. Identification of cellular deoxyhypusine synthase as a novel target for antiretroviral therapy. J. Clin. Invest. 115: 76-85, 2005.

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21003337-1	A02106-2	-	100 ug	$370		Add to Cart
BHA21003337-2	A02106-2-10ug	Sample	10 ug	$99		Add to Cart
BHA21003337-3	A02106-2-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21003337-4	A02106-2-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21003337-5	A02106-2-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21003337-6	A02106-2-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21003337-7	A02106-2-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21003337-8	A02106-2-FITC	FITC	100 ug	$570		Add to Cart
BHA21003337-9	A02106-2-HRP	HRP	100 ug	$570		Add to Cart
BHA21003337-10	A02106-2-APC	APC	100 ug	$670		Add to Cart
BHA21003337-11	A02106-2-PE	PE	100 ug	$670		Add to Cart
BHA21003337-12	A02106-2-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21003337-13	A02106-2-carrier-free	carrier-free	100 ug	$370		Add to Cart

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