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Home / Primary Antibodies / Monoclonal Antibodies

Anti-DDX6 Antibody Picoband® (monoclonal, 8G6)

SKU : BHA21003406

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Mfr.No.	M03826-1, M03826-1-10ug, M03826-1-Biotin, M03826-1-Cy3, M03826-1-Dylight488, M03826-1-Dylight550, M03826-1-Dylight594, M03826-1-FITC, M03826-1-HRP, M03826-1-APC, M03826-1-PE, M03826-1-iFluor647, M03826-1-carrier-free
Alternative Names	ubiquitin like modifier activating enzyme 2
Background	DDX6 (DEAD/H BOX 6), also known as HLR2 or p54, is an enzyme that in humans is encoded by the DDX6 gene. DDX6 belongs to the DEAD box family of putative RNA helicases that contain a characteristic asp-glu-ala-asp (DEAD) box motif (Seto et al., 1995). Tunnacliffe et al. (1993) assigned the DDX6 gene more precisely using a panel of sequence tagged sites (STSs) representing 30 markers previously assigned to 11q23. Using mass spectroscopy, Fenger-Gron et al. (2005) found that RCK, EDC3 (YJDC), and HEDLS (RCD8) coimmunopurified with DCP1A and DCP2 from HEK293 cell lysates. Overexpression of DCP2, RCK, or EDC3 in HeLa cells reduced the association of endogenous DCP1A and XRN1 with cytoplasmic P bodies.
Clonality	Monoclonal
Cross Reactivity	No cross-reactivity with other proteins.
Description	Boster Bio Anti-DDX6 Antibody Picoband® (monoclonal, 8G6) catalog # M03826-1. Tested in Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/S
Host	Mouse
Immunogen Region	E.coli-derived human DDX6 recombinant protein (Position: Q56-P483).
Isotype	Mouse IgG2b
Molecular Weight	54 kDa
Reactivity	Human, Mouse, Rat
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Synonyms	SUMO-activating enzyme subunit 2; Anthracycline-associated resistance ARX; Ubiquitin-like 1-activating enzyme E1B; Ubiquitin-like modifier-activating enzyme 2; UBA2; SAE2, UBLE1B; HRIHFB2115
Note	Each vial contains 4mg Trehalose, 0.9mg NaCl and 0.2mg Na2HPO4.

Uniprot	P26196
Gene Id	1656
Gene Name	DDX6
Clone No	Clone: 8G6
Subcellular Location	Nucleus; Cytoplasm

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	WB, ICC, IF, Flow Cytometry
Description	Weste blot, 0.25-0.5ug/ml, Human, Mouse, Rat<br> Immunocytochemistry/Immunofluorescence, 5ug/ml, Human<br> Flow Cytometry (Fixed), 1-3ug/1x10<sup>6</sup> cells, Human<br>

Reference	1. Fenger-Gron, M., Fillman, C., Norrild, B., Lykke-Andersen, J. Multiple processing body factors and the ARE binding protein TTP activate mRNA decapping. Molec. Cell 20: 905-915, 2005.<br /><br />2. Seto, M., Yamamoto, K., Takahashi, T., Ueda, R. Cloning and expression of a murine cDNA homologous to the human RCK/P54, a lymphoma-linked chromosomal translocation junction gene on 11q23. Gene 166: 293-296, 1995.<br /><br />3. Tunnacliffe, A., Perry, H., Radice, P., Budarf, M. L., Emanuel, B. S. A panel of sequence tagged sites for chromosome band 11q23. Genomics 17: 744-747, 1993.

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21003406-1	M03826-1	-	100 ug	$370		Add to Cart
BHA21003406-2	M03826-1-10ug	Sample	10 ug	$99		Add to Cart
BHA21003406-3	M03826-1-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21003406-4	M03826-1-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21003406-5	M03826-1-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21003406-6	M03826-1-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21003406-7	M03826-1-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21003406-8	M03826-1-FITC	FITC	100 ug	$570		Add to Cart
BHA21003406-9	M03826-1-HRP	HRP	100 ug	$570		Add to Cart
BHA21003406-10	M03826-1-APC	APC	100 ug	$670		Add to Cart
BHA21003406-11	M03826-1-PE	PE	100 ug	$670		Add to Cart
BHA21003406-12	M03826-1-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21003406-13	M03826-1-carrier-free	carrier-free	100 ug	$370		Add to Cart

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