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Home / Antibodies

Anti-Cytokeratin 18 Antibody

SKU : BHA10903471

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Applied Biological Materials (abm) Inc.

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Mfr.No.	Y300133
Categories	Primary Antibodies
Clonality	monoclonal
Description	Encoded by the KRT18 gene, the protein recognized by this antibody is the type I intermediate filament chain keratin 18. With Cytokeratin 8, Cytokeratin 18 is expressed in single layer epithelial tissues of the body and are involved in interleukin-6 (IL-6)-mediated barrier protection. When phosphorylated, Cytokeratin 18 also plays a role in filament reorganization. Diseases related to this gene include cryptogenic cirrhosis and non-alcoholic steatohepatitis. The Anti-Cytokeratin 18 Antibody does not react with stratified squamous epithelia but reacts with epithelial tumors of the gastrointestinal tract, lung, breast, pancreas, ovary, and thyroid. This antibody is also useful in studies which involve differentiating cells of epithelial origin from hematopoietic cells.
Host	Mouse
Immunogen	PMC-42 human breast carcinoma cells
Isotype	IgG1
Reactivity	Human
Recombinant	FALSE
Regulatory	RUO

Buffer	PBS, pH 7.4 with 0.05% sodium azide
Concentration	100µg/100µl
Description	Specificity: Human Cytokeratin 18 polypeptide.
Format	Liquid
Purity	The antibody was affinity-purified from hybridoma supernatant by affinity-chromatography.
Storage	This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20°C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.

Applications	IHC
Description	Use at an assay dependent concentration., IHC

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SKU	Supplier No.	Size	Your price	Quantity
BHA10903471	Y300133	100 ul	$322.50		Add to Cart

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