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Home / Primary Antibodies

Anti-Cysteinyl Leukotriene Receptor 1 Antibody

BHA10916322
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Contact us to order
Tel
+1 866.986.9598
Email
orders@biohippo.com
Get a Quote
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Buffer PBS, pH 7.4 with 0.02% sodium azide.
Concentration 100µg/100ul
Description Specificity: This Polyclonal antibody is directed against human Cysteinyl Leukotriene Receptor 1 protein. The product was purified from serum by Antigen Affinity Purify. Expect reactivity with human Cysteinyl Leukotriene Receptor 1.
Relevance: The cysteinyl leukotrienes (CysLTs; LTC4, LTD4, and LTE4) contract airway and pulmonary vascular smooth muscle, increase vascular permeability, and stimulate mucus secretion, thereby playing a major role in asthma.LTC4, LTD4, and LTE4 mediate their actions via at least two receptors designated CysLT1 and CysLT2. Cloning of the human CysLT1 receptor reveals it is a 337 amino acid protein with a calculated molecular mass of 38,549.5 The rank order of binding for leukotrienes to the cloned receptor, as determined using a radioligand binding assay, is LTD4 >> LTC4 = LTE4 >> LTB4.5 The mRNA for the human CysLT1 receptor is expressed in spleen and peripheral blood leukocytes with smaller amounts in lung, placenta, and small intestine. Immunohistochemical studies reveal the receptor is expressed on eosinophils, mast cells, macrophages, neutrophils, and vascular endothelial cells in the nasal mucosa.
Format Liquid
Purity Affinity purified
Storage This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20°C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.
Storage Condition -20C
Applications WB
Description Recommended dilutions
WB: 1/1000~4000
Predicted molecular weight: 39 kDa.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user., WB
Dilution

WB1:1000~4000
SKU Supplier No. Size Your price Quantity
BHA10916322 Y080062 100 ul $187.50
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