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Home / Antibodies

Anti-CysLT2 Receptor Antibody

BHA10918194
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Contact us to order
Tel
+1 866.986.9598
Email
orders@biohippo.com
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Buffer PBS, pH 7.4 with 0.02% sodium azide.
Concentration 100µg/100ul
Description Specificity: This Polyclonal antibody is directed against human CysLT2 Receptor protein. The product was purified from serum by protein A chromatography. Expect reactivity with human CysLT2 Receptor. Cross-reactivity with CysLT2 Receptor from other sources has not been determined.
Relevance: The cysteinyl leukotrienes (cysLTs; LTC4, LTD4, and LTE4) contract airway and pulmonary vascular smooth muscle, increase vascular permeability, and stimulate mucus secretion, thereby playing a major role in asthma.LTC4, LTD4, and LTE4 mediate their actions via at least two receptors designated CysLT1 and CysLT2. Cloning of the human CysLT2 receptor reveals it is a 346 amino acid protein with 38% homology to the CysLT1 receptor.The rank order of binding for leukotrienes to the cloned receptor, as determined using a radioligand binding assay, is LTC4 = LTD4 >> LTE The mRNA for the human CysLT2 receptor is expressed in lung macrophages, airway smooth muscle, cardiac Purkinje cells, adrenal medulla cells, peripheral blood leukocytes, spleen, placenta, and brain.
Format Liquid
Purity Affinity purified
Storage This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20°C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.
Storage Condition -20C
Applications WB
Description Recommended dilutions
WB: 1/1000~4000
Predicted molecular weight: 40 kDa.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user., WB
Dilution

WB1:1000~4000
SKU Supplier No. Size Your price Quantity
BHA10918194 Y080073 100 ul $187.50
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