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Home / Primary Antibodies / Polyclonal Antibodies

Anti-CYP1B1 Antibody Picoband®

SKU : BHA21006030

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Mfr.No.	A00515, A00515-10ug, A00515-Biotin, A00515-Cy3, A00515-Dylight488, A00515-Dylight550, A00515-Dylight594, A00515-FITC, A00515-HRP, A00515-APC, A00515-PE, A00515-iFluor647, A00515-carrier-free
Alternative Names	Serine/threonine-protein kinase AtPK1/AtPK6
Background	Cytochrome P450 1B1 is an enzyme that in humans is encoded by the CYP1B1 gene. CYP1B1 belongs to the the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The enzyme encoded by this gene localizes to the endoplasmic reticulum and metabolizes procarcinogens such as polycyclic aromatic hydrocarbons and 17beta-estradiol. Mutations in this gene have been associated with primary congenital glaucoma; therefore it is thought that the enzyme also metabolizes a signaling molecule involved in eye development, possibly a steroid.
Clonality	Polyclonal
Cross Reactivity	No cross reactivity with other proteins.
Description	Boster Bio Anti-CYP1B1 Antibody Picoband® catalog # A00515. Tested in WB, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Downstream effector of TOR signaling pathway involved in osmotic stress response. Could be involved in the control of plant growth and development. Phosphorylates the ribosomal proteins P14, P16 and S6. Functions as a repressor of cell proliferation and r
Host	Rabbit
Immunogen Region	E.coli-derived human CYP1B1 recombinant protein (Position: R255-E540). Human CYP1B1 shares 82.9% amino acid (aa) sequence identity with mouse and rat CYP1B1.
Isotype	IgG
Molecular Weight	52 kDa
Reactivity	Human, Mouse
Reconstitution	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Synonyms	70 kDa ribosomal protein S6 kinase 1 antibody, KS6B1_HUMAN antibody, p70 alpha antibody, P70 beta 1 antibody, p70 ribosomal S6 kinase alpha antibody, p70 ribosomal S6 kinase beta 1 antibody, p70 S6 kinase alpha antibody, P70 S6 Kinase antibody, p70 S6 kinase alpha 1 antibody, p70 S6 kinase alpha 2 antibody, p70 S6K antibody, p70 S6K-alpha antibody, p70 S6KA antibody, p70(S6K) alpha antibody, p70(S6K)-alpha antibody, p70-alpha antibody, p70-S6K 1 antibody, p70-S6K antibody, P70S6K antibody, P70S6K1 antibody, p70S6Kb antibody, PS6K antibody, Ribosomal protein S6 kinase 70kDa polypeptide 1 antibody, Ribosomal protein S6 kinase beta 1 antibody, Ribosomal protein S6 kinase beta-1 antibody, Ribosomal protein S6 kinase I antibody, RPS6KB1 antibody, S6K antibody, S6K-beta-1 antibody, S6K1 antibody, Serine/threonine kinase 14 alpha antibody, Serine/threonine-protein kinase 14A antibody, STK14A antibody
Tissue Specificity	Expressed in all tissues.
Note	Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Uniprot	Q16678
Gene Id	1545
Gene Name	CYP1B1
Subcellular Location	Cytoplasm. Nucleus.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months.Avoid repeated freezing and thawing.

Applications	WB, Flow Cytometry, ELISA
Description	Weste blot, 0.25-0.5 ug/ml, Human, Mouse Flow Cytometry (Fixed), 1-3 ug/1x10⁶ cells, Human ELISA, 0.1-0.5 ug/ml, -

Reference	1. "Entrez Gene: cytochrome P450". 2. Bailey LR, Roodi N, Dupont WD, Parl FF (1998). "Association of cytochrome P450 1B1 (CYP1B1) polymorphism with steroid receptor status in breast cancer.". Cancer Res. 58 (22): 503841. 3. Michels-Rautenstrauss KG, Mardin CY, Zenker M et al. (2002). "Primary congenital glaucoma: three case reports on novel mutations and combinations of mutations in the GLC3A (CYP1B1) gene.". J. Glaucoma 10 (4): 3547.

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21006030-1	A00515	-	100 ug	$370		Add to Cart
BHA21006030-2	A00515-10ug	Sample	10 ug	$99		Add to Cart
BHA21006030-3	A00515-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21006030-4	A00515-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21006030-5	A00515-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21006030-6	A00515-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21006030-7	A00515-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21006030-8	A00515-FITC	FITC	100 ug	$570		Add to Cart
BHA21006030-9	A00515-HRP	HRP	100 ug	$570		Add to Cart
BHA21006030-10	A00515-APC	APC	100 ug	$670		Add to Cart
BHA21006030-11	A00515-PE	PE	100 ug	$670		Add to Cart
BHA21006030-12	A00515-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21006030-13	A00515-carrier-free	carrier-free	100 ug	$370		Add to Cart

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