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Home / Antibodies

Anti-Cyclin D1 Antibody

SKU : BHA10902588

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Applied Biological Materials (abm) Inc.

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Mfr.No.	Y300121
Categories	Primary Antibodies
Clonality	monoclonal
Description	The DMITF1 encodes a transcription factor that contains a cyclin-D binding domain. Expression of this gene is frequently reduced in 40% of human non-small-cell lung carcinomas due to hemizygous gene deletion, strongly suggesting that this locus is haploinsufficient for tumor suppression. The Cyclin D1 is induced by the oncogenic Ras signalling pathway and functions as a tumor suppressor by activating the transcription of ARF to arrest cell growth or induce apoptosis. Other diseases related with the DMITF1 gene include parathyroid adenomas and mantle-cell lymphoma (MCL). The Anti-Cyclin D1 Antibody is a useful tool in cancer research particularly in studying oncogenesis.
Host	Mouse
Immunogen	Recombinant protein corresponding to human Cyclin D1
Isotype	IgG2a
Reactivity	Human
Recombinant	TRUE
Regulatory	RUO

Buffer	PBS, pH 7.4 with 0.05% sodium azide
Concentration	100µg/100µl
Description	Specificity: Anti-Cyclin D1 Antibody recognizes human Cyclin D1
Format	Liquid
Purity	The antibody was affinity-purified from hybridoma supernatant by affinity-chromatography.
Storage	This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20°C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.

Applications

WB, IP, IHC

Description

WB: 1:10000~1:50000; IP: 1:30; IHC: 1:100~1:500. Optimal dilutions should be calculated by the end user based on their specific application., WB ; IP ; IHC

Dilution

WB	1:10000-1:50000
IP	1:30
IHC	1:100-1:500

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SKU	Supplier No.	Size	Your price	Quantity
BHA10902588	Y300121	100 ul	$322.50		Add to Cart

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