Encoded by the CTLA4 gene, Cytotoxic T-Lymphocyte Antigen 4 (CTLA-4), also known as CD152, is a protein that functions in immune system regulation. It is expressed on the surface of helper T cells and transmits and inhibitory signal to T cells. Diseases associated with the CTLA4 gene include various autoimmune diseases, such as systemic lupus erythematosus, and insulin-dependent diabetes mellitus.
Host
Mouse
Immunogen
Spleen cells fused with Sp2/0-Ag14 cells
Isotype
IgG2a Kappa
Reactivity
Human
Recombinant
TRUE
Regulatory
RUO
Buffer
PBS, pH 7.4 with 0.05% sodium azide
Concentration
100µg/100µl
Description
Specificity: Human CTLA-4/CD152.
Format
Liquid
Purity
The antibody was affinity-purified from hybridoma supernatant by affinity-chromatography.
Storage
This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20°C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.