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Home / Primary Antibodies / Monoclonal Antibodies

Anti-CSF1R antibody(DM108), Rabbit mAb

SKU : BHA18100282

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DIMA Biotechnology

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Mfr.No.	DME100108
Background	The protein encoded by this gene is the receptor for colony stimulating factor 1, a cytokine which controls the production, differentiation, and function of macrophages. This receptor mediates most if not all of the biological effects of this cytokine. Ligand binding actIVates the receptor kinase through a process of oligomerization and transphosphorylation. The encoded protein is a tyrosine kinase transmembrane receptor and member of the CSF1/PDGF receptor family of tyrosine-protein kinases. Mutations in this gene have been associated with a predisposition to myeloid malignancy. The first intron of this gene contains a transcriptionally inactIVe ribosomal protein L7 processed pseudogene oriented in the opposite direction. AlternatIVe splicing results in multiple transcript variants. EXpression of a splice variant from an LTR promoter has been found in Hodgkin lymphoma (HL), HL cell lines and anaplastic large cell lymphoma.
Clonality	Monoclonal
Host	Rabbit
Isotype	Rabbit IgG
Reactivity	Human
Solubility	ELISA 1/5000-10000;Flow Cyt 1/100
Synonyms	CSF1R,C-FMS,CD115,CSFR,FIM2,FMS,M-CSFR
Usage	Research use only

Form	Powder
Purification	Purified from cell culture supernatant by affinity chromatography
Storage	Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).

Applications	ELISA,Flow Cyt

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SKU	Supplier No.	Size	Your price	Quantity
BHA18100282	DME100108	100 ug	$398		Add to Cart
BHA18100282	DME100108	10 ug	$60		Add to Cart

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