This gene encodes a plasma glycoprotein that positively regulates the alternative complement pathway of the innate immune system. This protein binds to many microbial surfaces and apoptotic cells and stabilizes the C3- and C5-convertase enzyme complexes in a feedback loop that ultimately leads to formation of the membrane attack complex and lysis of the target cell. Mutations in this gene result in two forms of properdin deficiency, which results in high susceptibility to meningococcal infections. Multiple alternatively spliced variants, encoding the same protein, have been identified.[provided by RefSeq, Feb 2009]
Formulation
Liquid
Host
Mouse(Mu)
Guarantee
abm guarantees that all our Anti-CFP Tag Antibody (Monoclonal) will perform as described on this product webpage, if this is not the case we will provide you with a one-time replacement at no extra cost. Documentation and explanation of experiment conducted will be required when submitting a claim for replacement.
Immunogen
GFP from the jellyfish Aequorea victoria N-Terminal peptide-KLH conjugates (first 20 aa)
Isotype
IgG
Quantity
1.0 mg
Recommended Dilution
WB 1:1000. For other applications, the researcher should determine the optimal working dilution.
Relevance
Has sensitivity of 1-10ng of purified GFP or GFP fusion protein (from a western blot developed with ECL)
Shipping Condition
Ice Packs
Specificity
Recognizes native and denatured forms of GFP and its variants EGFP, YFP, EYFP, and CFP.
Gene Name
CFP
Clone No
1218
Concentration
100µg/100ul
Purity
Affinity purified
Storage
This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20°C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.