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Home / Primary Antibodies

Anti-CDK6 (phospho-Tyr13) Antibody

SKU : BHA10917860

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Applied Biological Materials (abm) Inc.

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Mfr.No.	Y011542
Categories	Primary Antibodies ; Phospho Antibodies
Clonality	polyclonal
Description	The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This kinase is a catalytic subunit of the protein kinase complex that is important for cell cycle G1 phase progression and G1/S transition. The activity of this kinase first appears in mid-G1 phase, which is controlled by the regulatory subunits including D-type cyclins and members of INK4 family of CDK inhibitors. This kinase, as well as CDK4, has been shown to phosphorylate, and thus regulate the activity of, tumor suppressor protein Rb. Expression of this gene is up-regulated in some types of cancer. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Nov 2009]
Host	Rabbit
Immunogen	The antibody was produced against synthesized phosphopeptide derived from human CDK6 around the phosphorylation site of tyrosine 13 (Q-Q-YP-E-C).
Isotype	IgG
Quantity	100 µg
Reactivity	Mouse, Human
Recombinant	FALSE
Regulatory	RUO
Shipping Condition	Ice Packs

Buffer	Rabbit IgG in phosphate buffered saline (without Mg²+ and Ca²+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration	100µg/100ul
Description	Specificity: CDK6 (phospho-Tyr13) Antibody detects endogenous levels of CDK6 only when phosphorylated at tyrosine 13.
Format	Liquid
Purity	Affinity purified
Storage	This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20°C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.
Storage Condition	-20C

Applications

IF, IHC

Description

IHC: 1:50~100 IF:1:100~1:200, IF ; IHC

Dilution

IHC	1:50~100
IF	1:100-1:200~

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SKU	Supplier No.	Size	Your price	Quantity
BHA10917860	Y011542	100 ug	$427.50		Add to Cart

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