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Home / Primary Antibodies / Polyclonal Antibodies

Anti-CD80 Antibody Picoband®

SKU : BHA21006748

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Mfr.No.	PA1365-1, PA1365-1-10ug, PA1365-1-Biotin, PA1365-1-Cy3, PA1365-1-Dylight488, PA1365-1-Dylight550, PA1365-1-Dylight594, PA1365-1-FITC, PA1365-1-HRP, PA1365-1-APC, PA1365-1-PE, PA1365-1-iFluor647, PA1365-1-carrier-free
Alternative Names	CD80 molecule
Background	Cluster of Differentiation 80 (also CD80 and B7-1) is a protein found on activated B cells and monocytes that provides a costimulatory signal necessary for T cell activation and survival. It is the ligand for two different proteins on the T cell surface: CD28 (for autoregulation and intercellular association) and CTLA-4 (for attenuation of regulation and cellular disassociation). CD80 works in tandem with CD86 to prime T cells. The CD80 genes encode B7-1 which are structurally similar members of the immunoglobulin superfamily expressed on a variety of hematopoietic cell types. Reeves et al. (1997) stated that B7-1 and B7-2 provide a costimulatory signal to T cells by interacting with CD28 and CTLA4.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins
Description	Boster Bio Anti-CD80 Antibody catalog # PA1365-1. Tested in WB applications. This antibody reacts with Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Host	Rabbit
Immunogen Region	A synthetic peptide corresponding to a sequence at the C-terminus of rat CD80, different from the related mouse sequence by two amino acids.
Isotype	Rabbit IgG
Molecular Weight	50 kDa
Reactivity	Rat
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	CD80 ;
Note	Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Uniprot	O55202
Gene Name	CD80

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	WB
Description	Weste blot, 0.1-0.5ug/ml, Rat<br>

Reference	1. Peach, R J; Bajorath J, Naemura J, Leytze G, Greene J, Aruffo A, Linsley P S (Sep. 1995). "Both extracellular immunoglobin-like domains of CD80 contain residues critical for binding T cell surface receptors CTLA-4 and CD28". J. Biol. Chem. (UNITED STATES) 270 (36): 211817.<br /><br />2. Stamper, C C; Zhang Y, Tobin J F, Erbe D V, Ikemizu S, Davis S J, Stahl M L, Seehra J, Somers W S, Mosyak L (Mar. 2001). "Crystal structure of the B7-1/CTLA-4 complex that inhibits human immune responses". Nature (England) 410 (6828): 60811.<br /><br />

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21006748-1	PA1365-1	-	100 ug	$370		Add to Cart
BHA21006748-2	PA1365-1-10ug	Sample	10 ug	$99		Add to Cart
BHA21006748-3	PA1365-1-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21006748-4	PA1365-1-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21006748-5	PA1365-1-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21006748-6	PA1365-1-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21006748-7	PA1365-1-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21006748-8	PA1365-1-FITC	FITC	100 ug	$570		Add to Cart
BHA21006748-9	PA1365-1-HRP	HRP	100 ug	$570		Add to Cart
BHA21006748-10	PA1365-1-APC	APC	100 ug	$670		Add to Cart
BHA21006748-11	PA1365-1-PE	PE	100 ug	$670		Add to Cart
BHA21006748-12	PA1365-1-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21006748-13	PA1365-1-carrier-free	carrier-free	100 ug	$370		Add to Cart

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