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Home / Primary Antibodies

Anti-CD59 Antibody

SKU : BHA10902115

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Applied Biological Materials (abm) Inc.

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Mfr.No.	Y158048
Categories	Primary Antibodies
Clonality	polyclonal
Description	This gene encodes a cell surface glycoprotein that regulates complement-mediated cell lysis, and it is involved in lymphocyte signal transduction. This protein is a potent inhibitor of the complement membrane attack complex, whereby it binds complement C8 and/or C9 during the assembly of this complex, thereby inhibiting the incorporation of multiple copies of C9 into the complex, which is necessary for osmolytic pore formation. This protein also plays a role in signal transduction pathways in the activation of T cells. Mutations in this gene cause CD59 deficiency, a disease resulting in hemolytic anemia and thrombosis, and which causes cerebral infarction. Multiple alternatively spliced transcript variants, which encode the same protein, have been identified for this gene. [provided by RefSeq, Jul 2008]
Host	Rabbit
Immunogen	Rabbit polyclonal CD59 (1) antibody was raised against a recombinate human CD59 protein 29-102aa (BC001506).
Quantity	100 µl
Reactivity	Rat, Mouse, Human
Recombinant	FALSE
Regulatory	RUO
Shipping Condition	Ice Packs

Buffer	PBS, pH 7.4 with 0.02% Sodium Azide
Concentration	100µg/100ul
Description	Specificity: Human and predicted against mouse and rat.
Format	Liquid
Purity	Affinity purified
Storage	This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20°C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.
Storage Condition	-20C

Applications	IHC, ELISA
Description	IHC ; ELISA

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SKU	Supplier No.	Size	Your price	Quantity
BHA10902115	Y158048	100 ul	$217.50		Add to Cart

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