Synthetic peptide derived from Human CB1 Receptor.
Isotype
IgG
Quantity
100 µl
Reactivity
Rat, Human
Recombinant
FALSE
Regulatory
RUO
Shipping Condition
Ice Packs
Buffer
PBS, pH 7.4 with 0.02% sodium azide.
Concentration
100µg/100ul
Description
Specificity: This Polyclonal antibody is directed against human CB1 Receptor protein. The product was purified from serum by protein A chromatography. Expect reactivity with human CB1 Receptor. Cross-reactivity with CB1 Receptor from other sources has not been determined.Relevance: The CB1 receptor is a G-protein coupled receptor that binds the active component of cannabis, Δ9-tetrahydrocannabinol. This antibody has been raised against the C-terminal (amino acids 461-472) intracellular region of the human CB1receptor and can be used for western blotting(1).Human and rat CB1 receptors exhibit 97.3% homology at the amino acid level over the complete protein, and 100% homology within the peptide sequence used to make this antibody. This peptide exhibits no homology with the CB2 receptor. Based on the amino acid sequence, the CB1 receptor has a molecular weight of approximately 52,800(2). The CB1 receptor and the splice variant CB1a are localized mainly in the brain, whereas the CB2 receptor is localized predominantly in peripheral tissues, including the spleen and hemopoietic cells(3,4).
Format
Liquid
Purity
Affinity purified
Storage
This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20°C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.
Storage Condition
-20C
Applications
WB
Description
Recommended dilutionsWB: 1/500~5000Predicted molecular weight: 53 kDa.Not yet tested in other applications.Optimal dilutions/concentrations should be determined by the end user., WB