Caveolin 1: cell membrane, Caveolin 3: Membrane protein of caveolae.
Clonality
polyclonal
Description
Rabbit polyclonal to Caveolin 1/3
Host
Rabbit
Immunogen
Synthetic peptide derived from Human Caveolin 1/3.
Isotype
IgG
Quantity
100 µl
Reactivity
Rat, Mouse, Human
Recombinant
FALSE
Regulatory
RUO
Shipping Condition
Ice Packs
Buffer
PBS, pH 7.4 with 0.02% sodium azide.
Concentration
100µg/100ul
Description
Specificity: This Polyclonal antibody is directed against human Caveolin 1/3 protein. The product was purified from serum by protein A chromatography. Expect reactivity with human, murine and rat Caveolin 1/3. Cross-reactivity with Caveolin 1/3 from other sources has not been determined.Relevance: Caveolae are specialized domains of the plasma membrane that are implicated in the sequestration of a variety of lipid and protein molecules. It has been suggested that these important cellular organelles have a pivotal role in such diverse biochemical processes as lipid metabolism, growth regulation, signal transduction, and apoptosis. Caveolin interacts with and regulates heterotrimeric G-proteins. Currently, there are three members of the caveolin multigene family which are known to encode 21-24 kDa integral membrane proteins that comprise the major structural component of the caveolar membrane in vivo. Caveolin-2 protein is abundantly expressed in fibroblasts and differentiated adipocytes, smooth and skeletal muscle, and endothelial cells. The expression of caveolin-1 is similar to that of caveolin-2 while caveolin-3 expression appears to be limited to muscle tissue types.
Format
Liquid
Purity
Affinity purified
Storage
This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20°C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.
Storage Condition
-20C
Applications
WB
Description
Recommended dilutionsWB: 1/1000~4000Predicted molecular weight: 20/17 kDa.Not yet tested in other applications.Optimal dilutions/concentrations should be determined by the end user., WB
Dilution
WB
1:1000~4000
Reviews of Anti-Caveolin 1/3(Caveolin 1+ Caveolin 3) Antibody