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Home / Primary Antibodies / Polyclonal Antibodies

Anti-C5a-R/C5ar1 Antibody Picoband®

SKU : BHA21002810

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Mfr.No.	A01898-2, A01898-2-10ug, A01898-2-Biotin, A01898-2-Cy3, A01898-2-Dylight488, A01898-2-Dylight550, A01898-2-Dylight594, A01898-2-FITC, A01898-2-HRP, A01898-2-APC, A01898-2-PE, A01898-2-iFluor647, A01898-2-carrier-free
Alternative Names	C-C chemokine receptor type 1
Background	The C5a receptor also known as complement component 5a receptor 1 (C5AR1) or CD88 (Cluster of Differentiation 88) is a G protein-coupled receptor for C5a. It functions as a complement receptor. C5a receptor modulates inflammatory responses, obesity, development and cancers.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins.
Description	Boster Bio Anti-C5a-R/C5ar1 Antibody Picoband® catalog # A01898-2. Tested in ELISA, Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Mouse. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Receptor for a C-C type chemokine. Binds to MIP-1-alpha, RANTES, and less efficiently, to MIP-1-beta or MCP-1 and subsequently transduces a signal by increasing the intracellular calcium ions level. Responsible for affecting stem cell proliferation.
Host	Rabbit
Immunogen Region	E.coli-derived mouse C5a-R/C5ar1 recombinant protein (Position: H29-D327).
Isotype	Rabbit IgG
Molecular Weight	43 kDa
Reactivity	Mouse
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Synonyms	C-C chemokine receptor type 1;C-C CKR-1;CC-CKR-1;CCR-1;CCR1;Macrophage inflammatory protein 1-alpha receptor;MIP-1alpha-R;RANTES-R;CD191;Ccr1;Cmkbr1;
Tissue Specificity	Detected in the heart, spleen, lung, peritoneal exudate cells and leukocytes.
Note	Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.01mg NaN3.

Uniprot	P30993
Gene Id	12273
Gene Name	C5ar1
Subcellular Location	Cell membrane; Multi-pass membrane protein.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	WB, ICC, IF, Flow Cytometry, ELISA
Description	Weste blot, 0.25-0.5ug/ml, Mouse<br> Immunocytochemistry/Immunofluorescence, 5ug/ml, Mouse<br> Flow Cytometry (Fixed), 1-3ug/1x10<sup>6</sup> cells, Mouse<br> ELISA, 0.1-0.5ug/ml, -<br>

Reference	1. Arbore, G., West, E. E., Spolski, R., Robertson, A. A. B., Klos, A., Rheinheimer, C., Dutow, P., Woodruff, T. M., Yu, Z. X., O'Neill, L. A., Coll, R. C., Sher, A., and 10 others. T helper 1 immunity requires complement-driven NLRP3 inflammasome activity in CD4+ T cells. Science 352: aad1210, 2016<br /><br />2. Atkinson, J. P. Complement system on the attack in autoimmunity. (Commentary) J. Clin. Invest. 112: 1639-1641, 2003.<br /><br />3. Bao, L., Gerard, N. P., Eddy, R. L., Jr., Shows, T. B., Gerard, C. Mapping of genes for the human C5a receptor (C5AR), human FMLP receptor (FPR), and two FMLP receptor homologue orphan receptors (FPRH1, FPRH2) to chromosome 19. Genomics 13: 437-440, 1992.

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21002810-1	A01898-2	-	100 ug	$370		Add to Cart
BHA21002810-2	A01898-2-10ug	Sample	10 ug	$99		Add to Cart
BHA21002810-3	A01898-2-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21002810-4	A01898-2-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21002810-5	A01898-2-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21002810-6	A01898-2-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21002810-7	A01898-2-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21002810-8	A01898-2-FITC	FITC	100 ug	$570		Add to Cart
BHA21002810-9	A01898-2-HRP	HRP	100 ug	$570		Add to Cart
BHA21002810-10	A01898-2-APC	APC	100 ug	$670		Add to Cart
BHA21002810-11	A01898-2-PE	PE	100 ug	$670		Add to Cart
BHA21002810-12	A01898-2-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21002810-13	A01898-2-carrier-free	carrier-free	100 ug	$370		Add to Cart

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