Anti-c-Myc Oncoprotein Antibody BHA10203610

Mfr.No.	4609-MSM6-P1ABX
Alternative Names	Class E basic helix-loop-helix protein 39 (bHLHe39) ; MRTL ; Myc2 ; Niard ; Nird ; Proto-oncogene c-Myc ; RNCMYC ; Transcription factor p64 ; Transcriptional regulator Myc-A ; V-Myc avian myelocytomatosis viral oncogene homolog
Categories	Primary Antibodies
Cellular Localization	Nuclear
Chromosome Location	8q24.21
Clonality	Monoclonal
Description	It recognizes a transcription factor of 64-67kDa, identified as c-myc. This MAb shows no cross-reaction with v-myc. c-myc is involved in the control of cell proliferation and differentiation and is amplified and/or over-expressed in a variety of tumors. Over-expression of c-myc protein occurs frequently in luminal cells of prostate intraepithelial neoplasia as well as in most primary carcinomas and metastatic disease. Rearrangement of the MYC gene is found in 3% to 16% of diffuse large B-cell lymphoma (DLBCL s) and in nearly 100% of Burkitt lymphomas (BL). Identifying MYC status is important in establishing final diagnosis of DLBCL, BL, or B-cell lymphoma, with features intermediate between DLBCL and BL as well as in differential diagnoses of the lymphomas.
Host	Mouse
Immunogen	Recombinant human c-myc protein
Isotype	IgG1 Kappa
Positive Control	HL-60 cells or Cervical Carcinoma
Reactivity	Human
Recombinant	FALSE
Regulatory	RUO

Swissprot	P01106
Uniprot	202453
Gene Id	4609

Buffer	200μg/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Concentration	1.0mg/ml
Description	There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Purity	Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Applications

FACS, IF, IHC-F

Description

(Staining of formalin-fixed tissues requires boiling tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 10-20 min followed by cooling at RT for 20 minutes);Optimal dilution for a specific application should be determined., FACS ; IF ; IHC-F

Dilution

FACS	0.5-1μg/million cells
IF	1-2μg/ml
IHC-F	1-2μg/ml for 30 minutes at RT

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SKU	Supplier No.	Size	Your price	Quantity
BHA10203610	4609-MSM6-P1ABX	100µg	$393.20		Add to Cart

Anti-c-Myc Oncoprotein Antibody BHA10203610

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