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Home / Primary Antibodies / Polyclonal Antibodies

Anti-c-Jun/JUN Antibody Picoband®

SKU : BHA21003430

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Mfr.No.	A02038-2, A02038-2-10ug, A02038-2-Biotin, A02038-2-Cy3, A02038-2-Dylight488, A02038-2-Dylight550, A02038-2-Dylight594, A02038-2-FITC, A02038-2-HRP, A02038-2-APC, A02038-2-PE, A02038-2-iFluor647, A02038-2-carrier-free
Alternative Names	transient receptor potential cation channel, subfamily C, member 4
Background	c-Jun is a protein that in humans is encoded by the JUN gene. This gene is the putative transforming gene of avian sarcoma virus 17. It encodes a protein which is highly similar to the viral protein, and which interacts ly with specific target DNA sequences to regulate gene expression. This gene is intronless and is mapped to 1p32-p31, a chromosomal region involved in both translocations and deletions in human malignancies.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins.
Description	Boster Bio Anti-c-Jun/JUN Antibody Picoband® catalog # A02038-2. Tested in IF, IHC, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Form a receptor-activated non-selective calcium permeant cation channel. Acts as a cell-cell contact-dependent endothelial calcium entry channel. Probably operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or
Host	Rabbit
Immunogen Region	A synthetic peptide corresponding to a sequence in the middle region of human c-Jun/JUN, which shares 93.3% amino acid (aa) sequence identity with both mouse and rat c-Jun/JUN.
Isotype	Rabbit IgG
Molecular Weight	43 kDa
Reactivity	Human
Reconstitution	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Synonyms	Short transient receptor potential channel 4; TrpC4; Trp-related protein 4; hTrp-4; hTrp4; TRPC4
Tissue Specificity	Strongly expressed in placenta. Expressed at lower levels in heart, pancreas, kidney and brain. Expressed in endothelial cells. Isoform alpha was found to be the predominant isoform. Isoform beta was not found in pancreas and brain.
Note	Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Uniprot	P05412
Gene Id	3725
Gene Name	JUN
Subcellular Location	Membrane; Enhanced insertion into the cell membrane after activation of the EGF receptor.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Applications	WB, IHC, ICC, IF
Description	Weste blot, 0.25-0.5 ug/ml, Human<br> Immunohistochemistry(Paraffin-embedded Section), 2-5 ug/ml, Human<br> Immunocytochemistry/Immunofluorescence, 5 ug/ml, Human<br>

Reference	1. Aguilera, C., Nakagawa, K., Sancho, R., Chakraborty, A., Hendrich, B., Behrens, A. c-Jun N-terminal phosphorylation antagonises recruitment of the Mbd3/NuRD repressor complex. Nature 469: 231-235, 2011. <br /><br />2. Bahary, N., Zorich, G., Pachter, J. E., Leibel, R. L., Friedman, J. M. Molecular genetic linkage maps of mouse chromosomes 4 and 6. Genomics 11: 33-47, 1991. <br /><br />3. Behrens, A., Sibilia, M., Wagner, E. F. Amino-terminal phosphorylation of c-Jun regulates stress-induced apoptosis and cellular proliferation. Nature Genet. 21: 326-329, 1999.

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21003430-1	A02038-2	-	100 ug	$370		Add to Cart
BHA21003430-2	A02038-2-10ug	Sample	10 ug	$99		Add to Cart
BHA21003430-3	A02038-2-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21003430-4	A02038-2-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21003430-5	A02038-2-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21003430-6	A02038-2-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21003430-7	A02038-2-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21003430-8	A02038-2-FITC	FITC	100 ug	$570		Add to Cart
BHA21003430-9	A02038-2-HRP	HRP	100 ug	$570		Add to Cart
BHA21003430-10	A02038-2-APC	APC	100 ug	$670		Add to Cart
BHA21003430-11	A02038-2-PE	PE	100 ug	$670		Add to Cart
BHA21003430-12	A02038-2-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21003430-13	A02038-2-carrier-free	carrier-free	100 ug	$370		Add to Cart

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