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Home / Primary Antibodies

Anti-BRCA1 (Ab-1524) Antibody

SKU : BHA10916882

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Applied Biological Materials (abm) Inc.

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Mfr.No.	Y021139
Categories	Primary Antibodies
Clonality	polyclonal
Description	A reciprocal translocation between chromosomes 22 and 9 produces the Philadelphia chromosome, which is often found in patients with chronic myelogenous leukemia. The chromosome 22 breakpoint for this translocation is located within the BCR gene. The translocation produces a fusion protein which is encoded by sequence from both BCR and ABL, the gene at the chromosome 9 breakpoint. Although the BCR-ABL fusion protein has been extensively studied, the function of the normal BCR gene product is not clear. The protein has serine/threonine kinase activity and is a GTPase-activating protein for p21rac. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Host	Rabbit
Immunogen	The antibody was produced against synthesized non-phosphopeptide derived from human BRCA1 around the phosphorylation site of serine 1524 (Y-P-SP-Q-E).
Isotype	IgG
Quantity	100 µg
Reactivity	Human
Recombinant	FALSE
Regulatory	RUO
Shipping Condition	Ice Packs

Buffer	Rabbit IgG in phosphate buffered saline (without Mg²+ and Ca²+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration	100µg/100ul
Description	Specificity: BRCA1 (Ab-1524) Antibody detects endogenous levels of total BRCA1protein.
Format	Liquid
Purity	Affinity purified
Storage	This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20°C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.
Storage Condition	-20C

Applications

IP

Description

IF:1:100~1:200, IP

Dilution

IF	1:100-1:200~

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SKU	Supplier No.	Size	Your price	Quantity
BHA10916882	Y021139	100 ug	$427.50		Add to Cart

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