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Home / Primary Antibodies / Monoclonal Antibodies

Anti-BRAF V600E Antibody

SKU : BHA14800142

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GenomeMe Lab Inc

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Mfr.No.	IHC600-7
Clonality	Monoclonal
Description	Serine/Threonine-Protein Kinase B-Raf (BRAF) is a cytoplasmic serine-threonine kinase of the RAF family, which mediates downstream cellular responses to growth signals through the mitogen-activated protein kinase (MAPK) signaling pathway. Oncogenic mutations in the BRAF gene, 80% of which are a single V600E substitution within the kinase domain, constitutively activate the MAPK signaling pathway and result in increased cell proliferation and apoptosis resistance. The V600E mutation is observed in colorectal cancer, non-Hodgkin's lymphoma, papillary thyroid carcinoma, malignant melanoma, non-small-cell lung carcinoma, and lung adenocarcinoma. BRAF V600E is therefore an important immunohistochemical marker for tumour diagnosis and prognosis.
Host	Mouse
Isotype	IgG2b
Species	Human

Clone No	IHC600

Buffer	Tris Buffer pH7.6 with BSA, and sodium azide as preservative
Storage	-20 degrees Celsius

Applications	WB, IHC, ELISA
Dilution	1:200

Product Manual	MSDS

No Description Available.

GeneAbﾙ BRAF V600E [IHC600] on Thyroid Papillary Carcinoma with the BRAF V600E Mutation

No Description Available.

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SKU	Supplier No.	Size	Your price	Quantity
BHA14800142	IHC600-7	7ml RTU Predilute	$310		Add to Cart
BHA14800142	IHC600-7	100ul Concentrate	$210		Add to Cart
BHA14800142	IHC600-7	1ml Concentrate	$1250		Add to Cart

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