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Home / Primary Antibodies

Anti-BLT2 receptor Antibody

BHA10918718
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Tel
+1 866.986.9598
Email
orders@biohippo.com
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Buffer PBS, pH 7.4 with 0.02% sodium azide.
Concentration 100µg/100ul
Description Specificity: This Polyclonal antibody is directed against human BLT2 receptor protein. The product was purified from serum by protein A chromatography. Cross-reactivity with BLT2 receptor from other sources has not been determined.
Relevance: Leukotriene B4 (LTB4) promotes a number of leukocyte functions including aggregation, stimulation of ion fluxes, superoxide anion production, chemotaxis, and chemokinesis. Two G-protein coupled receptors, BLT1 and BLT2, which mediate the actions of LTB4 have been cloned and characterized(1). The BLT1 receptor is expressed in leukocytes, U937 cells, and to a much lower extent in spleen and thymus.4 The human BLT2 receptor is a 358 amino acid protein with approximately 40% homology to BLT1 at the amino acid level. The BLT2 receptor is more broadly expressed than the BLT1 receptor, with highest levels observed in liver, spleen, ovary, intestine, and peripheral blood leukocytes(2). Activation of the BLT2 receptor by LTB4 leads to Ca2+ mobilization as well as decreases in cyclic AMP, indicating interaction of the receptor with Gq and Gi classes of G-proteins(3).
Format Liquid
Purity Affinity purified
Storage This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20°C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.
Storage Condition -20C
Applications WB
Description Recommended dilutions
WB: 1/2000.
Predicted molecular weight: 43 kDa.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user., WB
Dilution

WB1:2000
SKU Supplier No. Size Your price Quantity
BHA10918718 Y080029 100 ul $187.50
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