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Home / Primary Antibodies / Monoclonal Antibodies

Anti-Beta-Catenin

SKU : BHA15100276

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BioGenex Laboratories

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Mfr.No.	AN778-5M
Clonality	Monoclonal
Description	Beta-Catenin is a regulatory protein of Wnt pathway with key roles in cell adhesion and signal transduction, development, cellular proliferation, and differentiation. Mutations of Beta-Catenin gene are commonly found in a variety of cancers: in primary hepatocellular carcinoma, colorectal cancer, ovarial carcinoma, breast cancer, lung cancer and glioblastoma. Mutations occuring in the Beta-Catenin gene CTNNB1 leads to stabilization of Beta-Catenin in the cytoplasm and translocation to the nucleus have been implicated in various forms of tumor including familial adenomatous polyposis, fibromatosis, solitary fibrous tumors and endometrial carcinoma. A nuclear accumulation of Beta-Catenin in fibromatosis (desmoid tumor) in various locations including breast and mesentery is useful in the differentiation of this tumor from other fibroblast like lesions
Host	Rabbit
Isotype	IgG
Reactivity	Human
Species	Rabbit

Clone No	EP35
Research Area	Infectious diseases, Immune system

Buffer	PBS
Concentration	1-3ug/ml
Storage	2-8°C

Applications	IHC
Dilution	1:10-20

Product Manual	Datasheet SDS

No Description Available.

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Combination SKU	Supplier No.	Size	Your price	Quantity
AN778-5M	AN778-5M	6 mL	$217		Add to Cart
AN778-10M	AN778-10M	100 tests - i6000	$412		Add to Cart
AY778-50D	AY778-50D	50 tests - Xmatrx	$242		Add to Cart
AY778-YCD	AY778-YCD	160 tests - Xmatrx	$654		Add to Cart
NU778-UC	NU778-UC	1ml Conc	$361		Add to Cart
NU778-5UC	NU778-5UC	0.5ml Conc	$254		Add to Cart

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