Anti-beta-Catenin Antibody

Mfr.No.	Y300107
Categories	Primary Antibodies
Clonality	monoclonal
Description	β-Catenin is a part of a complex of proteins that constitute adherens junctions (AJs), which are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. It is also the key downstream component of the canonical Wnt signaling pathway. β-Catenin anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. It binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in this gene are a cause of colorectal cancer (CRC), pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer. Other diseases associated with CTNNB1 include Colorectal Adenomatous Polyposis, Autosomal Recessive, With Pilomatricomas and Mental Retardation, Autosomal Dominant 19.
Host	Mouse
Immunogen	Purified recombinant full length human β-Catenin expressed in E. coli
Isotype	IgG1
Reactivity	Human
Recombinant	FALSE
Regulatory	RUO

Buffer	PBS, pH 7.4 with 0.05% sodium azide
Concentration	100µg/100µl
Description	Specificity: Human β-Catenin
Format	Liquid
Purity	The antibody was affinity-purified from hybridoma supernatant by affinity-chromatography.
Storage	This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20°C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.

Applications

WB, IF, IHC, ELISA

Description

WB: 1:2000~1:5000
ELISA: 1:1000~1:5000
IHC: 1:200~1:500
IF: 1:200~1:500
Optimal dilutions should be calculated by the end user based on their specific application., WB ; IF ; IHC ; ELISA

Dilution

WB	1:2000-1:5000
ELISA	1:1000-1:5000
IHC	1:200-1:500
IF	1:200-1:500

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SKU	Supplier No.	Size	Your price	Quantity
BHA10916537	Y300107	100 ul	$322.50		Add to Cart

Anti-beta-Catenin Antibody

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