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Home / Primary Antibodies

Anti-ATF4 (Phospho-Ser245) Antibody

SKU : BHA10916079

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Applied Biological Materials (abm) Inc.

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Mfr.No.	Y011053
Categories	Primary Antibodies ; Phospho Antibodies
Clonality	polyclonal
Description	This gene encodes a transcription factor that was originally identified as a widely expressed mammalian DNA binding protein that could bind a tax-responsive enhancer element in the LTR of HTLV-1. The encoded protein was also isolated and characterized as the cAMP-response element binding protein 2 (CREB-2). The protein encoded by this gene belongs to a family of DNA-binding proteins that includes the AP-1 family of transcription factors, cAMP-response element binding proteins (CREBs) and CREB-like proteins. These transcription factors share a leucine zipper region that is involved in protein-protein interactions, located C-terminal to a stretch of basic amino acids that functions as a DNA binding domain. Two alternative transcripts encoding the same protein have been described. Two pseudogenes are located on the X chromosome at q28 in a region containing a large inverted duplication. [provided by RefSeq, Sep 2011]
Host	Rabbit
Immunogen	The antiserum was produced against synthesized phosphopeptide derived from human ATF4 around the phosphorylation site of serine 245 (N-R-SP-L-P).
Quantity	100 µg
Reactivity	Human
Recombinant	FALSE
Regulatory	RUO
Shipping Condition	Ice Packs

Buffer	phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration	1µg/ul
Description	Specificity: ATF4 (phospho-Ser245) antibody detects endogenous levels of ATF4 only when phosphorylated at serine 245.
Format	Liquid
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatogramphy using non-phosphopeptide corresponding to the phosphorylation site.
Storage	This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20°C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.
Storage Condition	-20C

Applications

IHC

Description

IHC: 1:50~1:100, IHC

Dilution

IHC	1:50-1:100~

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SKU	Supplier No.	Size	Your price	Quantity
BHA10916079	Y011053	100 ug	$427.50		Add to Cart

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