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Home / Primary Antibodies / Polyclonal Antibodies

Anti-ATF1 Antibody Picoband®

SKU : BHA21000054

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Mfr.No.	PB9130, PB9130-10ug, PB9130-Biotin, PB9130-Cy3, PB9130-Dylight488, PB9130-Dylight550, PB9130-Dylight594, PB9130-FITC, PB9130-HRP, PB9130-APC, PB9130-PE, PB9130-iFluor647, PB9130-carrier-free
Alternative Names	Cyclic AMP-dependent transcription factor ATF-1
Background	ATF1, also known as activating transcription factor 1, is a protein that in humans is encoded by the ATF1 gene. It is mapped to 12q13.12. This gene encodes an activating transcription factor, which belongs to the ATF subfamily and bZIP (basic-region leucine zipper) family. It influences cellular physiologic processes by regulating the expression of downstream target genes, which are related to growth, survival, and other cellular activities. This protein is phosphorylated at serine 63 in its kinase-inducible domain by serine/threonine kinases, cAMP-dependent protein kinase A, calmodulin-dependent protein kinase I/II, mitogen- and stress-activated protein kinase and cyclin-dependent kinase 3 (cdk-3). Its phosphorylation enhances its transactivation and transcriptional activities, and enhances cell transformation.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins
Description	Boster Bio Anti-ATF1 Antibody Picoband® catalog # PB9130. Tested in Flow Cytometry, IHC, WB applications. This antibody reacts with HumanThe brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	This protein binds the cAMP response element (CRE) (consensus: 5'-GTGACGT(AC)(AG)-3'), a sequence present in many viral and cellular promoters. Binds to the Tax-responsive element (TRE) of HTLV-I. Mediates PKA-induced stimulation of CRE-reporter genes. Re
Host	Rabbit
Immunogen Region	E.coli-derived human ATF1 recombinant protein (Position: M1-V271). Human ATF1 shares 91% amino acid (aa) sequence identity with mouse ATF1.
Isotype	Rabbit IgG
Molecular Weight	38 kDa
Reactivity	Human
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	Cyclic AMP-dependent transcription factor ATF-1;cAMP-dependent transcription factor ATF-1;Activating transcription factor 1;Protein TREB36;ATF1;
Tissue Specificity	Ubiquitously expressed, with highest levels in lung, kidney, heart, gastrointestinal system and prostate. Isoform Testis-specific is expressed in spermatocytes and adult testis. .
Note	Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Uniprot	P18846
Gene Id	466
Gene Name	ATF1
Sequence	Belongs to the bZIP family. ATF subfamily.
Subcellular Location	Nucleus.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	Flow Cytometry, IHC, WB
Description	Weste blot, 0.1-0.5ug/ml, Human Immunohistochemistry (Paraffin-embedded Section), 0.5-1ug/ml, Human, By Heat Flow Cytometry (Fixed), 1-3ug/1x10⁶ cells, Human

Reference	1. ucman, J., Delattre, O., Desmaze, C., Epstein, A. L., Stenman, G., Speleman, F., Fletchers, C. D. M., Aurias, A., Thomas, G. EWS and ATF-1 gene fusion induced by t(12;22) translocation in malignant melanoma of soft parts. Nature Genet. 4: 341-345, 1993. 2. "Entrez Gene: ATF1 activating transcription factor 1"

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Combination SKU	Supplier No.	Size	Conjugation	Your price	Quantity
BHA21000054-1	PB9130	100 ug	-	$370		Add to Cart
BHA21000054-3	PB9130-Biotin	100 ug	Biotin	$570		Add to Cart
BHA21000054-4	PB9130-Cy3	100 ug	Cy3	$570		Add to Cart
BHA21000054-5	PB9130-Dylight488	100 ug	Dylight488	$570		Add to Cart
BHA21000054-6	PB9130-Dylight550	100 ug	Dylight550	$570		Add to Cart
BHA21000054-7	PB9130-Dylight594	100 ug	Dylight594	$570		Add to Cart
BHA21000054-8	PB9130-FITC	100 ug	FITC	$570		Add to Cart
BHA21000054-9	PB9130-HRP	100 ug	HRP	$570		Add to Cart
BHA21000054-10	PB9130-APC	100 ug	APC	$670		Add to Cart
BHA21000054-11	PB9130-PE	100 ug	PE	$670		Add to Cart
BHA21000054-12	PB9130-iFluor647	100 ug	iFluor647	$670		Add to Cart
BHA21000054-13	PB9130-carrier-free	100 ug	carrier-free	$370		Add to Cart
BHA21000054-2	PB9130-10ug	10 ug	Sample	$99		Add to Cart

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