ASAH3(N-acylsphingosine amidohydrolase 3) or CER1(alkaline ceramidase) deacylates ceramide to generate sphingosine and a fatty acid. Ceramidases deacylate ceramides, important intermediates in the metabolic pathway of sphingolipids. CER1 is selectively expressed in skin and may have a role in regulating the levels of bioactive lipids ceramide and S1P, as well as complex sphingolipids.
Host
Rabbit
Immunogen
Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to N-terminal residues of human ASAH3(N-acylsphingosine amidohydrolase 3) or CER1(alkaline ceramidase)
Isotype
IgG
Quantity
100 µg
Reactivity
Human
Recombinant
FALSE
Regulatory
RUO
Shipping Condition
Ice Packs
Buffer
PBS, pH 7.4 with 0.05% sodium azide.
Concentration
1µg/ul
Format
Liquid
Purity
Purified by antigen-specific affinity chromatography.
Storage
This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20°C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.
Storage Condition
-20C
Applications
WB, ELISA
Description
WB ; ELISA
Reviews of Anti-ASAH3(N-acylsphingosine amidohydrolase 3) Antibody