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Home / Primary Antibodies

Anti-APP (Phospho-Thr668) Antibody

SKU : BHA10915982

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Applied Biological Materials (abm) Inc.

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Mfr.No.	Y011190
Categories	Primary Antibodies ; Phospho Antibodies
Clonality	polyclonal
Description	This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Host	Rabbit
Immunogen	The antiserum was produced against synthesized phosphopeptide derived from human APP around the phosphorylation site of threonine 668 (A-V-TP-P-E).
Quantity	100 µg
Reactivity	Rat, Mouse, Human
Recombinant	FALSE
Regulatory	RUO
Shipping Condition	Ice Packs

Buffer	phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration	1µg/ul
Description	Specificity: APP (Phospho-Thr668) antibody detects endogenous levels of APP only when phosphorylated at threonine 668
Format	Liquid
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Storage	This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20°C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.
Storage Condition	-20C

Applications

WB

Description

WB: 1:500~1:1000, WB

Dilution

WB	1:500-1:1000~

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SKU	Supplier No.	Size	Your price	Quantity
BHA10915982	Y011190	100 ug	$427.50		Add to Cart

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