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Home / Primary Antibodies

Anti-APEX2 Antibody

SKU : BHA10917423

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Applied Biological Materials (abm) Inc.

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Mfr.No.	Y058378
Categories	Primary Antibodies
Cellular Localization	Nuclear
Clonality	polyclonal
Description	Apurinic/apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. AP sites are pre-mutagenic lesions that can prevent normal DNA replication so the cell contains systems to identify and repair such sites. Class II AP endonucleases cleave the phosphodiester backbone 5' to the AP site. This gene encodes a protein shown to have a weak class II AP endonuclease activity. Most of the encoded protein is located in the nucleus but some is also present in mitochondria. This protein may play an important role in both nuclear and mitochondrial base excision repair. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2012]
Host	Rabbit
Immunogen	Rabbit polyclonal APEX2 antibody was raised against a peptide at the C terminal residues of human APEX2 protein.
Isotype	IgG
Quantity	100 µl
Reactivity	Human
Recombinant	TRUE
Regulatory	RUO
Shipping Condition	Ice Packs

Buffer	PBS, pH 7.4 with 0.02% Sodium Azide
Concentration	100µg/100ul
Format	Liquid
Purity	Affinity purified
Storage	This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20°C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.
Storage Condition	-20C

Applications

IHC, ELISA

Description

For research use only
Peptide ELISA titer: 1:1,000-1:10,000
Immunohistochemistry: 1:50-200
Optimal dilutions/concentrations should be determined by the end use, IHC ; ELISA

Dilution

ELISA	1:1,000-1:10,000
IHC	1:50-200

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SKU	Supplier No.	Size	Your price	Quantity
BHA10917423	Y058378	100 ul	$217.50		Add to Cart

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