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Home / Antibodies

Anti-Annexin A1 Antibody

SKU : BHA10902563

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Applied Biological Materials (abm) Inc.

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Mfr.No.	Y300103
Categories	Primary Antibodies
Clonality	monoclonal
Description	Encoded by ANXA1 gene, Annexin A1 is a Ca2+-dependent membrane-localized protein that binds phospholipids. This protein inhibits phospholipase A2, which is required for the biosynthesis of the potent mediators of inflammation, prostaglandins and leukotrienes. Thus, Annexin A1 plays important roles in the innate immune response as effector of glucocorticoid-mediated responses and regulator of the inflammatory process, promoting resolution of inflammation and wound healing. It also contributes to the adaptive immune response by enhancing signaling cascades that are triggered by T-cell activation, regulates differentiation and proliferation of activated T-cells. Loss of function or expression of the gene has been detected in multiple tumors. The antibody recognizes human annexin A1 amino acids 41 - 118, and specifically inhibits Annexin A1 mediated phospholipid vesicle aggregation.
Host	Mouse
Immunogen	Annexin A1 protein isolated from human polymorphonuclear leukocytes
Isotype	IgG1
Reactivity	Human
Recombinant	FALSE
Regulatory	RUO

Buffer	PBS, pH 7.4 with 0.05% sodium azide
Concentration	100µg/100µl
Description	Specificity: Human Annexin A1 amino acids 41 – 118
Format	Liquid
Purity	The antibody was affinity-purified from hybridoma supernatant by affinity-chromatography.
Storage	This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20°C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.

Applications

WB, ELISA

Description

WB: 1:500~1:1000
ELISA: 1:500~1:1000
Optimal dilutions should be calculated by the end user based on their specific application., WB ; ELISA

Dilution

WB	1:500-1:1000~
ELISA	1:500~

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SKU	Supplier No.	Size	Your price	Quantity
BHA10902563	Y300103	100 ul	$322.50		Add to Cart

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