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Home / Primary Antibodies

Anti-Aldosterone-3 Antibody

SKU : BHA10901003

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Applied Biological Materials (abm) Inc.

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Mfr.No.	Y030103
Categories	Primary Antibodies
Clonality	monoclonal
Description	Aldosterone-3 is a The major mineralcorticoid, which is secreted almost independently of ACTH from the pitutitary, is aldosterone. Aldosterone secretion is controlled mostly by the levels of potassium and sodium in serum and a blood pressure control system called the renin-angiotensin system. The principle action of aldosterone is the retention of sodium. Where sodium goes, so goes associated ions and water. Therefore, aldosterone profoundly effects fluid balance by effecting intracellular and extracellular fluid volume. Aldosterone has the opposite effect on serum levels of potassium as it is lost in the urine in exchange for sodium in the renal tubules. Salivary and sweat glands are also influenced by aldosterone to save sodium and the intestine increases the absorption of sodium in response to aldosterone. Aldosterone levels increase and cause fluid retention in diseases such as congestive heart failure and liver cirrhosis. Certain diuretics act by antagonizing aldosterone. In contrast to most diuretics that cause potassium loss, the aldosterone antagonists increase blood potassium and are sometimes used for this effect.
Host	Mouse
Immunogen	BSA conjugate of the 3-O carboxylmethyl oxime of aldosterone.
Isotype	IgG1
Quantity	100 µl
Reactivity	Human
Recombinant	TRUE
Regulatory	RUO
Shipping Condition	Ice Packs

Buffer	PBS, pH 7.4 with 0.02% sodium azide.
Concentration	100µg/100ul
Description	Specificity: The antibody is highly specific for aldosterone and does not cross-react significantly with other steroids. The antibody displays low cross-reactivity with 18-hydroxycorticosterone and 18-hydroxydeoxycorticosterone and showed no detectable displacement of tritiated aldosterone from the antibodies with cortisol, corticosterone, and related steroids. The only steroid that showed moderate cross-reactivity was 3 alpha,5 beta-tetrahydroaldosterone (around 3%).
Format	Liquid
Purity	Affinity purified
Storage	This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20°C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.
Storage Condition	-20C

Applications	RIA
Description	RIA

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SKU	Supplier No.	Size	Your price	Quantity
BHA10901003	Y030103	100 ul	$382.50		Add to Cart

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