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Home / Primary Antibodies

Anti-AKAP13 Antibody

SKU : BHA10902863

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Applied Biological Materials (abm) Inc.

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Mfr.No.	Y058721
Categories	Primary Antibodies
Clonality	polyclonal
Description	The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms containing c-terminal dbl oncogene homology (DH) and pleckstrin homology (PH) domains. The DH domain is associated with guanine nucleotide exchange activation for the Rho/Rac family of small GTP binding proteins, resulting in the conversion of the inactive GTPase to the active form capable of transducing signals. The PH domain has multiple functions. Therefore, these isoforms function as scaffolding proteins to coordinate a Rho signaling pathway, function as protein kinase A-anchoring proteins and, in addition, enhance ligand-dependent activity of estrogen receptors alpha and beta. [provided by RefSeq, Jul 2012]
Host	Rabbit
Quantity	100 µg
Reactivity	Human
Recombinant	FALSE
Regulatory	RUO
Shipping Condition	Ice Packs

Buffer	PBS, pH 7.4 with 0.02% Sodium Azide
Concentration	100µg/100ul
Format	Liquid
Purity	Affinity purified
Storage	This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20°C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.
Storage Condition	-20C

Applications

WB, ELISA

Description

For research use only
ELISA titer: 1:20,000-1:80,000
Western blot analysis: 1:500-1:1,000
Optimal dilutions/concentrations should be determined by the end use, WB ; ELISA

Dilution

ELISA	1:20,000-1:80,000
WB	1:500-1:1,000

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SKU	Supplier No.	Size	Your price	Quantity
BHA10902863	Y058721	100 ug	$217.50		Add to Cart

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