This gene encodes a mitochondrially localized enzyme that catalyzes the reversible formation of acetoacetyl-CoA from two molecules of acetyl-CoA. Defects in this gene are associated with 3-ketothiolase deficiency, an inborn error of isoleucine catabolism characterized by urinary excretion of 2-methyl-3-hydroxybutyric acid, 2-methylacetoacetic acid, tiglylglycine, and butanone. [provided by RefSeq, Feb 2009] Annotation information: Note: ACAT1 (GeneID 38) and SOAT1 (GeneID 6646) loci share the ACAT1 symbol/alias in common. ACAT1 is widely used alternative name for acyl-Coenzyme A: cholesterol acyltransferase 1 (SOAT1) conflicting with the official symbol for acetyl-Coenzyme A acetyltransferase 1 (acetoacetyl Coenzyme A thiolase) (ACAT1). [04 Jun 2007]
Host
Mouse
Immunogen
N-terminal 104 amino acids of human ACAT1 protein.
Isotype
IgG
Quantity
100 µg
Reactivity
Human
Recombinant
FALSE
Regulatory
RUO
Shipping Condition
Ice Packs
Buffer
PBS, pH 7.4 with 0.05% sodium azide.
Concentration
100µg/100ul
Description
Specificity: Recognize specifically human ACAT1 and other species not tested.
Format
Liquid
Storage
This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20°C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.
Storage Condition
-20C
Applications
WB, ELISA
Description
Western Blot (1:1000) and ELISA (1:2000 ~ 5000)., WB ; ELISA