Specificity: This affinity purified antibody is directed against human ACAT 2. The product was affinity purified from antiserum by immunoaffinity purification. Cross-reactivity with ACAT 2 from other sources has not been determined.Relevance: Acyl-Coenzyme A: cholesterol acyltransferase-2 (ACAT-2) catalyzes the formation of cholesterol esters from cholesterol and long chain fatty acyl-coenzyme A. It is associated with lipoprotein particle secretion and thus plays an important role in the metabolism of triglyceride-rich lipoproteins like ApoB100(1).In humans, ACAT-2 is primarily expressed in the small intestine, whereas in other mammals, the enzyme is expressed in the liver and the small intestine(2). Human ACAT-2 has 522 amino acid with an estimated molecular weight of 60 kDa.
Format
Liquid
Purity
Affinity purified
Storage
This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20°C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.
Storage Condition
-20C
Applications
WB
Description
Recommended dilutionsWB: 1/1000.Predicted molecular weight: 60 kDa.Not yet tested in other applications.Optimal dilutions/concentrations should be determined by the end user., WB