Anti-ABCA1 Antibody

Mfr.No.	G090
Categories	Primary Antibodies
Clonality	monoclonal
Description	Mutations in the ABCA1 gene (ATP-binding cassette transporter 1) are associated with Tangier disease (TD). TD is an autosomal recessive disorder results from an absence of plasma HDL, cholesterol ester depositing in the reticulo-endothelial system and disorders in cellular lipid trafficking. It is expressed on the plasma membrane and the Golgi complex, and is regulated by cholesterol flux. Regulation of the cholesterol flux between HDL and macrophages is competitive between ABCA1 and SR-BI.
Host	Mouse
Immunogen	Peptides amino acids 1800-2260 (C-Terminal end)
Isotype	IgG
Quantity	100 µg
Reactivity	Mouse, Human
Recombinant	FALSE
Regulatory	RUO
Shipping Condition	Ice Packs

Buffer	PBS, pH 7.4 with 0.05% sodium azide.
Concentration	100µg/100ul
Description	Specificity: Recognize specifically ABCA1 from human, mouse, and chicken.
Format	Liquid
Storage	This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20°C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.
Storage Condition	-20C

Applications

WB, IP, IHC, ELISA

Description

Starting concentration for WB is 1:1000. This antibody has been tested with direct ELISA, where a 96-well plate was coated with recombinant ABCA1 C-terminal protein. The antibody was then added to the wells and a goat anti-mouse IgG HRP conjugate was used for colour development. For ABCA1 quantification, a pair of anti-ABCA1 antibodies should be used to formulate a Sandwich ELISA and with a presence of an ABCA1 protein Standard. Optimal dilution to be determined by the end user., WB ; IP ; IHC ; ELISA

Dilution

1:1000

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SKU	Supplier No.	Size	Your price	Quantity
BHA10918649	G090	100 ug	$322.50		Add to Cart

Anti-ABCA1 Antibody

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