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Home / Primary Antibodies / Polyclonal Antibodies

Anti-12 Lipoxygenase/ALOX12 UBB Antibody Picoband®

SKU : BHA21000030

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Mfr.No.	PA1485-1, PA1485-1-10ug, PA1485-1-Biotin, PA1485-1-Cy3, PA1485-1-Dylight488, PA1485-1-Dylight550, PA1485-1-Dylight594, PA1485-1-FITC, PA1485-1-HRP, PA1485-1-APC, PA1485-1-PE, PA1485-1-iFluor647, PA1485-1-carrier-free
Alternative Names	Polyubiquitin-B
Background	ALOX12, Arachidonate 12-lipoxygenase, is an enzyme that in humans is encoded by the ALOX12 gene. By fluorescence in situ hybridization, the ALOX12 gene is located in band 17p13.1. The gene consists of 14 exons with 13 introns and spans approximately 15 kb of DNAArachidonate 12-lipoxygenase introduces a molecular oxygen into the C-12 position of arachidonic acid to produce 12 (S)-hydroperoxy-5,8,10,14-eicosatetraenoic acid. The major pathway of arachidonic acid metabolism in human platelets proceeds via a 12-lipoxygenase enzyme. Expression of the LOG12 gene was detected in human erythroleukemia cells, platelets, and human umbilical vein endothelial cells by reverse transcription-PCR analysis.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins
Description	Boster Bio Anti-12 Lipoxygenase/ALOX12 UBB Antibody catalog # PA1485-1. Tested in WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Ubiquitin: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of th
Host	Rabbit
Immunogen Region	A synthetic peptide corresponding to a sequence at the C-terminus of human ALOX12, different from the related rat sequence by four amino acids, and from the related mouse sequence by five amino acids.
Isotype	Rabbit IgG
Molecular Weight	75 kDa
Reactivity	Human
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	Polyubiquitin-B;Ubiquitin;UBB;
Tissue Specificity	Expressed in vascular smooth muscle cells.
Note	Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Uniprot	P0CG47
Gene Name	ALOX12
Sequence	Belongs to the lipoxygenase family.
Subcellular Location	Ubiquitin: Cytoplasm . Nucleus .

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	WB
Description	Weste blot, 0.1-0.5ug/ml, Human

Reference	1. Funk, C. D., Furci, L., FitzGerald, G. A.Molecular cloning, primary structure, and expression of the human platelet/erythroleukemia cell 12-lipoxygenase.Proc. Nat. Acad. Sci. 87: 5638-5642, 1990. 2. Natarajan, R., Esworthy, R., Bai, W., Gu, J.-L., Wilczynski, S., Nadler, J.Increased 12-lipoxygenase expression in breast cancer tissues and cells. Regulation by epidermal growth factor.J. Clin. Endocr. Metab. 82: 1790-1798, 1997. 3. Yoshimoto, T., Arakawa, T., Hada, T., Yamamoto, S., Takahashi, E.Structure and chromosomal localization of human arachidonate 12-lipoxygenase gene.J. Biol. Chem. 267: 24805-24809, 1992.

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Combination SKU	Supplier No.	Size	Conjugation	Your price	Quantity
BHA21000030-1	PA1485-1	100 ug	-	$370		Add to Cart
BHA21000030-3	PA1485-1-Biotin	100 ug	Biotin	$570		Add to Cart
BHA21000030-4	PA1485-1-Cy3	100 ug	Cy3	$570		Add to Cart
BHA21000030-5	PA1485-1-Dylight488	100 ug	Dylight488	$570		Add to Cart
BHA21000030-6	PA1485-1-Dylight550	100 ug	Dylight550	$570		Add to Cart
BHA21000030-7	PA1485-1-Dylight594	100 ug	Dylight594	$570		Add to Cart
BHA21000030-8	PA1485-1-FITC	100 ug	FITC	$570		Add to Cart
BHA21000030-9	PA1485-1-HRP	100 ug	HRP	$570		Add to Cart
BHA21000030-10	PA1485-1-APC	100 ug	APC	$670		Add to Cart
BHA21000030-11	PA1485-1-PE	100 ug	PE	$670		Add to Cart
BHA21000030-12	PA1485-1-iFluor647	100 ug	iFluor647	$670		Add to Cart
BHA21000030-13	PA1485-1-carrier-free	100 ug	carrier-free	$370		Add to Cart
BHA21000030-2	PA1485-1-10ug	10 ug	Sample	$99		Add to Cart

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