Rabbit polyclonal to 11-Hydroxysteroid Dehydrogenase(Type 1)
Host
Rabbit
Immunogen
Synthetic peptide derived from Human 11-Hydroxysteroid Dehydrogenase(Type 1).
Isotype
IgG
Quantity
100 µl
Reactivity
Rat, Human
Recombinant
TRUE
Regulatory
RUO
Shipping Condition
Ice Packs
Buffer
PBS, pH 7.4 with 0.02% sodium azide.
Concentration
100µg/100ul
Description
Specificity: This Polyclonal antibody is directed against human 11-Hydroxysteroid Dehydrogenase(Type 1)protein. The product was purified from serum by protein A chromatography. Expect reactivity with human 11-Hydroxysteroid Dehydrogenase(Type 1). Cross-reactivity with 11-Hydroxysteroid Dehydrogenase(Type 1) from other sources has not been determined.Relevance: 11-Hydroxysteroid dehydrogenase(Type 1) catalyzes the conversion of inactive cortisone to active cortisol in adipose tissue. mRNA and protein for this enzyme have been detected in a wide range of tissues including liver, kidney, testis, lung, heart, and colon. The enzyme’s expression is developmentally regulated, suggesting its importance in regulation of glucocorticoid action during embryonic development. Over-expression of 11-Hydroxysteroid dehydrogenase (Type 1) results in visceral obesity and metabolic syndrome including insulin-resistant diabetes, hyperlipidemia, and hyperphagia. The 11-Hydroxysteroid dehydrogenase(Type 1) Polyclonal Antibody can be used for WB analysis for 11-Hydroxysteroid dehydrogenase(Type 1) on samples of human, murine, and rat origin. Other applications for use of this antibody have not yet been tested. The antibody detects a 30 kDa protein by WB analysis.
Format
Liquid
Purity
Affinity purified
Storage
This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20°C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.
Storage Condition
-20C
Applications
WB
Description
Recommended dilutionsWB: 1/500~3000Predicted molecular weight: 30 kDa.Not yet tested in other applications.Optimal dilutions/concentrations should be determined by the end user., WB
Dilution
WB
1:500~3000
Reviews of Anti-11-Hydroxysteroid Dehydrogenase(Type 1) Antibody