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Home / Antibodies

ACE Antibody / Angiotensin I Converting Enzyme (V8490)

SKU : BHA17118162

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Mfr.No.	V8490, V8490-20UG, V8490-100UG
Clonality	Monoclonal
Description	This gene encodes an enzyme involved in catalyzing the conversion of angiotensin I into a physiologically active peptide angiotensin II. Angiotensin II is a potent vasopressor and aldosterone-stimulating peptide that controls blood pressure and fluid-electrolyte balance. This enzyme plays a key role in the renin-angiotensin system. Many studies have associated the presence or absence of a 287 bp Alu repeat element in this gene with the levels of circulating enzyme or cardiovascular pathophysiologies. Two most abundant alternatively spliced variants of this gene encode two isozymes - the somatic form and the testicular form that are equally active. Multiple additional alternatively spliced variants have been identified but their full length nature has not been determined.
Formulation	0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Host	Mouse
Immunogen Region	A portion of amino acids 652-788 from the human protein was used as the immunogen for the ACE antibody.
Isotype	IgG2c,kappa
Predicted Reactivity	Human
Reactivity	Human
Recombinant	No
Subcellular Location	Cell surface, cytoplasm

Antigen	ACE
Uniprot	P12821
Clone No	ACE/3762

Concentration	0.2 mg/ml
Format	Purified
Purification	Protein G affinity chromatography
Storage	Store the ACE antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).

Applications	WB, ELISA, IHC-P
Dilution	Western blot: 1-2ug/ml,ELISA: order Ab without BSA for coating,Immunohistochemistry (FFPE): 1-2ug/ml for 30 minutes at RT

Product Manual	Data Sheet

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Combination SKU	Supplier No.	Size	Your price	Quantity
BHA17118162-1	V8490-20UG	20ug	$219		Add to Cart
BHA17118162-2	V8490-100UG	100ug	$499		Add to Cart

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