Transcription factor involved in epidermis differentiation. Required for terminal epidermal differentiation: acts downstream of p63/TP63 and activates expression of late epidermal differentiation genes. Specifically binds to the promoter of KLF4 and promotes its expression.
Categories
Primary Antibodies
Cellular Localization
Nucleus
Clonality
polyclonal
Description
Transcription factor involved in epidermis differentiation. Required for terminal epidermal differentiation: acts downstream of p63/TP63 and activates expression of late epidermal differentiation genes. Specifically binds to the promoter of KLF4 and promotes its expression.
Host
Rabbit
Immunogen
zinc finger protein 750
Isotype
IgG
Molecular Weight
77 kDa
Reactivity
Human, Mouse
Regulatory
RUO
Subcellular Location
Nucleus
Synonyms
ZNF750, Protein ZNF750, zinc finger protein 750, Zfp750, FLJ13841
Antigen
ZNF750
Uniprot
Q32MQ0
Gene Id
79755
Research Area
Metabolism
Weight
77kDa
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)