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Home / Primary Antibodies / Polyclonal Antibodies

ZIP8 antibody

SKU : BHA10809613

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Mfr.No.	FNab09643
Alternative Names	BIGM103 ; PP3105 ; SLC39A8 ; ZIP8 ; ZIP8
Background	SLC39A8 also known as ZIP8 belongs to the ZIP family of metal ion transporters which function to transport zinc and/or other metal ion substrates from the extracellular space or organellar lumen into the cytoplasm. Recently it was found that Zip8 expression is upregulated in human monocytes in response to LPS, TNF-alpha, and live bacteria, facilitating cytoprotection during the early inflammation. Besides zinc ZIP8 can also transport cadmium and manganese efficiently. It is predicted that ZIP8 contains 3 potential N-linked glycosylation sites and is subject to glycosylation, which may account for the presences of multiple molecular weights, such as 43 kDa, 49 kDa, 60 kDa, 75-90 kDa, 150 kDa, and 200 kDa.
Categories	Primary Antibodies
Cellular Localization	Membrane
Clonality	polyclonal
Description	SLC39A8 also known as ZIP8 belongs to the ZIP family of metal ion transporters which function to transport zinc and/or other metal ion substrates from the extracellular space or organellar lumen into the cytoplasm. Recently it was found that Zip8 expression is upregulated in human monocytes in response to LPS, TNF-α, and live bacteria, facilitating cytoprotection during the early inflammation. Besides zinc ZIP8 can also transport cadmium and manganese efficiently. It is predicted that ZIP8 contains 3 potential N-linked glycosylation sites and is subject to glycosylation, which may account for the presences of multiple molecular weights, such as 43 kDa, 49 kDa, 60 kDa, 75-90 kDa, 150 kDa, and 200 kDa.
Host	Rabbit
Immunogen	solute carrier family 39(zinc transporter), member 8
Isotype	IgG
Molecular Weight	53 kDa, 75-90 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Subcellular Location	membrane
Synonyms	BIGM103, PP3105, SLC39A8, ZIP 8, ZIP8

Antigen	ZIP8
Uniprot	Q9C0K1
Gene Id	64116
Research Area	Signal Transduction, Metabolism
Weight	50kDa,Observed 50kDa and 90kDa

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications

ELISA, WB, IHC, IF

Description

ELISA ; WB ; IHC ; IF

Dilution

WB	1:500-1:5000
IP	1:200-1:2000
IHC	1:20-1:200
IF	1:10-1:100

Tested Application

WB: 1:500-1:2000; IP: 1:200-1:2000; IHC: 1:20-1:200; IF: 1:10-1:100

Manual	FNab09643.pdf

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SKU	Supplier No.	Size	Your price	Quantity
BHA10809613	FNab09643	100ug	$260		Add to Cart

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