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Home / Primary Antibodies / Polyclonal Antibodies

ZEB2 Antibody / SIP1

SKU : BHA17105024

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NSJ Bioreagents

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Mfr.No.	R31649
Clonality	Polyclonal
Description	Zinc finger E-box-binding homeobox 2, also known as SIP1 or Zinc finger homeobox 1B (ZFHX1B), is a protein that in humans is encoded by the ZEB2 gene. The gene is a member of the ZEB1/Drosophila Zfh1 family of two-handed zinc finger/homeodomain proteins and functions as a DNA-binding transcriptional repressor that interacts with activated<a href=../search_result.php?search_txt=smad>SMADs</a>, the transducers of<a href=../search_result.php?search_txt=tgf beta>TGF-beta</a>signaling, and interacts with the nucleosome remodeling and histone deacetylation (NURD) complex. By radiation hybrid analysis, this gene is mapped to 2q22. It has been found that synthesis of ZEB2 was upregulated following<a href=../search_result.php?search_txt=snai1>SNAI1</a>expression in human cell lines, and the expression of SNAI1 in epithelial cells can trigger an epithelial-mesenchyme transition.
Formulation	0.5mg/ml if reconstituted with 0.2ml sterile DI water
Host	Rabbit
Immunogen Region	Human partial recombinant protein (AA 1-200) was used as the immunogen for this ZEB2 antibody.
Isotype	IgG
Predicted Reactivity	Human
Reactivity	Human
Recombinant	No

Antigen	ZEB2
Gene Id	9839

Format	Antigen affinity purified
Purification	Antigen affinity
Storage	After reconstitution, the ZEB2 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Applications	WB
Dilution	Western blot: 0.5-1ug/ml

Product Manual	Data Sheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA17105024	R31649	100ug	$439		Add to Cart

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