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Home / Primary Antibodies / Polyclonal Antibodies

XPG antibody

SKU : BHA10809518

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Mfr.No.	FNab09547
Alternative Names	COFS3 ; ERCC5 ; ERCM2 ; UVDR ; XPG ; XPGC
Background	The human genes correcting DNA repair defects are termed excision-repair cross-complementing or ERCC genes. The ERCC5 gene corrects the excision repair deficiency of Chinese hamster ovary cell line UV135 of complementation group 5. The human ERCC5 gene product is a structure-specific endonuclease required for making the 3-prime incision during DNA nucleotide excision-repair(NER). It also plays an important role in regulating DNA excision repair, removal of bulky lesions caused by environmental chemicals or UV light (PMID:22815677).
Categories	Primary Antibodies
Cellular Localization	Nucleus
Clonality	polyclonal
Description	The human genes correcting DNA repair defects are termed excision-repair cross-complementing or ERCC genes. The ERCC5 gene corrects the excision repair deficiency of Chinese hamster ovary cell line UV135 of complementation group 5. The human ERCC5 gene product is a structure-specific endonuclease required for making the 3-prime incision during DNA nucleotide excision-repair (NER). It also plays an important role in regulating DNA excision repair, removal of bulky lesions caused by environmental chemicals or UV light [PMID:22815677].
Host	Rabbit
Immunogen	excision repair cross-complementing rodent repair deficiency, complementation group 5
Isotype	IgG
Molecular Weight	200 kDa
Reactivity	Human
Regulatory	RUO
Subcellular Location	Nucleus
Synonyms	COFS3, ERCC5, ERCM2, UVDR, XPG, XPGC

Antigen	XPG
Uniprot	P28715
Research Area	Epigenetics, Metabolism
Weight	133kDa,Observed 200kDa

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications

ELISA, WB, IP

Description

ELISA ; WB ; IP

Dilution

WB	1:200-1:2000
IF	1:20-1:200
IP	1:200-1:2000

Tested Application

WB: 1:200-1:2000; IF: 1:20-1:200; IP: 1:200-1:2000

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SKU	Supplier No.	Size	Your price	Quantity
BHA10809518	FNab09547	100ug	$280		Add to Cart

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