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Home / Primary Antibodies / Polyclonal Antibodies

WDR5 antibody

SKU : BHA10809471

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Mfr.No.	FNab09497
Alternative Names	WDR5 ; BIG3 ; BMP2induced3kbgeneprotein ; WDrepeatcontainingprotein5 ; SWD3
Background	This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This protein contains 7 WD repeats. Alternatively spliced transcript variants encoding the same protein have been identified.
Categories	Primary Antibodies
Cellular Localization	Nucleus
Clonality	polyclonal
Description	Contributes to histone modification. May position the N- terminus of histone H3 for efficient trimethylation at 'Lys-4'. As part of the MLL1/MLL complex it is involved in methylation and dimethylation at 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. As part of the NSL complex it may be involved in acetylation of nucleosomal histone H4 on several lysine residues. May regulate osteoblasts differentiation.
Host	Rabbit
Immunogen	WD repeat domain 5
Isotype	IgG
Molecular Weight	37 kDa
Reactivity	Human, Mouse
Regulatory	RUO
Subcellular Location	Nucleus
Synonyms	WDR5, BIG3, BMP2 induced 3 kb gene protein, WD repeat containing protein 5, SWD3

Antigen	WDR5
Uniprot	P61964
Gene Id	11091
Research Area	Stem Cells, Metabolism
Weight	36kDa,observed 42kDa,36kDa

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Applications

ELISA, WB, IHC

Description

ELISA ; WB ; IHC

Dilution

WB	1:500-1:5000
IHC	1:20-1:200

Tested Application

WB: 1:500 - 1:2000; IHC: 1:50 - 1:200

Manual	FNab09497.pdf

No Description Available.

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SKU	Supplier No.	Size	Your price	Quantity
BHA10809471	FNab09497	100ug	$260		Add to Cart

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